DRE RECOMBINASE AND RECOMBINASE SYSTEMS EMPLOYING DRE RECOMBINASE

The invention provides a Dre/rox recombinase system. In particular, the invention provides Dre polypeptides that can catalyze site-specific recombination at rox sites but not at lox sites. The Dre/rox system can be utilized in a number of genetic manipulations either alone or in combination with oth...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MCDERMOTT, JEFFREY, SAUER, BRIAN L
Format: Patent
Sprache:eng ; fre
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides a Dre/rox recombinase system. In particular, the invention provides Dre polypeptides that can catalyze site-specific recombination at rox sites but not at lox sites. The Dre/rox system can be utilized in a number of genetic manipulations either alone or in combination with other recombinase systems. Système de recombinase Dre/rox, plus particulièrement polypeptides Dre susceptibles de catalyser une recombination spécifique au site en des sites rox. Le système Dre/rox est utilisé dans un certain nombre de manipulations génétiques seul ou combiné à d'autres systèmes de recombinase.