IDENTIFICATION OF REGIONS OF APICAL MEMBRANE ANTIGEN 1 OF APICOMPLEXAN PARASITES SUITABLE FOR TARGETING BY VACCINES AND DRUGS BY DERIVATION AND ANALYSIS OF THE THREE-DIMENSIONAL STRUCTURE

The present invention relates to a crystal of the ectoplasmic domain of Apical Membrane Protein 1 (AMA1) from Plasmodium and a method of crystallisation of such a protein. The invention is also directed to the crystal structure of this AMA1 domain and to the three-dimensional structure of the domain...

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Hauptverfasser: VULLIEZ-LE-NORMAND, BRIGITTE, BENTLEY, GRAHAM, THOMAS, ALAN, IGONET, SEBASTIEN, RIOTTOT, MARIE-MADELEINE, COLLINS, CHRISTINE, R, FAURE-KUZMINSKA, GRAZYNA, KOCKEN, CLEMENS, H., M, PIZARRO, JUAN CARLOS, BLACKMAN, MICHAEL, J
Format: Patent
Sprache:eng ; fre
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