IDENTIFICATION OF REGIONS OF APICAL MEMBRANE ANTIGEN 1 OF APICOMPLEXAN PARASITES SUITABLE FOR TARGETING BY VACCINES AND DRUGS BY DERIVATION AND ANALYSIS OF THE THREE-DIMENSIONAL STRUCTURE
The present invention relates to a crystal of the ectoplasmic domain of Apical Membrane Protein 1 (AMA1) from Plasmodium and a method of crystallisation of such a protein. The invention is also directed to the crystal structure of this AMA1 domain and to the three-dimensional structure of the domain...
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