THERAPEUTIC COMBINATIONS COMPRISING POLY(ADP-RIBOSE) POLYMERASES INHIBITOR

The invention generally relates to use of 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one represented by Formula (1) as a chemosensitizer that enhances the efficacy of cytotoxic drugs or radiotherapy. This invention provides pharmaceutical combinations of...

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Hauptverfasser: DEWJI, MOHAMED, RAZA, JONES, CHRISTOPHER, CURTIN, NICOLA, JANE, KLAMERUS, KAREN, J, WILLIAMS, KAYE, JANINE, BORITZKI, THEODORE, JAMES, PLUMMER, ELIZABETH, RUTH, REICH, STEVEN, DAVID, THOMAS, HUW, DAVID, STRATFORD, IAN, J, KAUFMAN, RHONDA, NEWELL, DAVID, RICHARD, HOSTOMSKY, ZDENEK, STEINFELDT, HEIDI, MARIE, CALVERT, ALAN, HILARY
Format: Patent
Sprache:eng ; fre
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