THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS

The use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R , R, R , R , R and R are as defined in the specification, in the preparation of a medicament for the treatment of C-C chemokine mediated conditions. Novel compounds of formula (I) and pharmaceuti...

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Hauptverfasser: BOWER, JUSTIN FAIRFIELD, HAMLIN, GORDON ALEXANDER, WINTER, JON
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creator BOWER, JUSTIN FAIRFIELD
HAMLIN, GORDON ALEXANDER
WINTER, JON
description The use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R , R, R , R , R and R are as defined in the specification, in the preparation of a medicament for the treatment of C-C chemokine mediated conditions. Novel compounds of formula (I) and pharmaceutical compositions containing them are also described and claimed. L'invention concerne l'utilisation d'un composé représenté par la formule générale (I) ou d'un de ses sels ou solvates de qualité pharmaceutique, dans la préparation d'un médicament destiné au traitement de troubles induits par la chimiokine CC. Dans cette formule, R , R, R , R , R et R désignent des éléments définis dans la description de la présente demande. L'invention concerne également de nouveaux composés représentés par la formule générale (I) et des compositions pharmaceutiques contenant ces composés.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS
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