PROCESS FOR CRYSTALLIZATION OF RAMIPRIL AND PREPARATION OF A HYDRATED FORM THEREOF
The present invention relates to a novel method for obtaining (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-amino] propanoyl] octahydro cyclopenta[b] pyrrole-2-carboxylic acid, viz. Ramipril(I) in high optical purity, free of other stereoisomers, and in high bulk density. The presen...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SINGH, GIRIJ, PAL RANANAWARE, UMESH, BABANRAO DHAKE, VILAS, NATHU |
| description | The present invention relates to a novel method for obtaining (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-amino] propanoyl] octahydro cyclopenta[b] pyrrole-2-carboxylic acid, viz. Ramipril(I) in high optical purity, free of other stereoisomers, and in high bulk density. The present invention also relates to a novel hydrated form of Ramipril(I) and a process for preparation thereof.
L'invention concerne un procédé d'élaboration d'acide (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(éthoxycarbonyle)-3-phénylpropyle]-amino] propanoyle] octahydro cyclopenta[b] pyrrole-2-carboxylique, à savoir Ramipril(I), de pureté optique élevée, sans autres stéréoisomères, et de poids volumétrique élevé. L'invention concerne également une forme hydratée de Ramipril(I) et un procédé d'élaboration correspondant. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2005068422A3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2005068422A3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2005068422A33</originalsourceid><addsrcrecordid>eNrjZAgKCPJ3dg0OVnDzD1JwDooMDnH08fGMcgzx9PdT8HdTCHL09QwI8vRRcPRzUQgIcg1wDILLOSp4RLoAua4uIN2-CiEerkGu_m48DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IwMDUwMzCxMjI0diYOFUAoxIwkg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR CRYSTALLIZATION OF RAMIPRIL AND PREPARATION OF A HYDRATED FORM THEREOF</title><source>esp@cenet</source><creator>SINGH, GIRIJ, PAL ; RANANAWARE, UMESH, BABANRAO ; DHAKE, VILAS, NATHU</creator><creatorcontrib>SINGH, GIRIJ, PAL ; RANANAWARE, UMESH, BABANRAO ; DHAKE, VILAS, NATHU</creatorcontrib><description>The present invention relates to a novel method for obtaining (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-amino] propanoyl] octahydro cyclopenta[b] pyrrole-2-carboxylic acid, viz. Ramipril(I) in high optical purity, free of other stereoisomers, and in high bulk density. The present invention also relates to a novel hydrated form of Ramipril(I) and a process for preparation thereof.
L'invention concerne un procédé d'élaboration d'acide (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(éthoxycarbonyle)-3-phénylpropyle]-amino] propanoyle] octahydro cyclopenta[b] pyrrole-2-carboxylique, à savoir Ramipril(I), de pureté optique élevée, sans autres stéréoisomères, et de poids volumétrique élevé. L'invention concerne également une forme hydratée de Ramipril(I) et un procédé d'élaboration correspondant.</description><edition>7</edition><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060119&DB=EPODOC&CC=WO&NR=2005068422A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060119&DB=EPODOC&CC=WO&NR=2005068422A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SINGH, GIRIJ, PAL</creatorcontrib><creatorcontrib>RANANAWARE, UMESH, BABANRAO</creatorcontrib><creatorcontrib>DHAKE, VILAS, NATHU</creatorcontrib><title>PROCESS FOR CRYSTALLIZATION OF RAMIPRIL AND PREPARATION OF A HYDRATED FORM THEREOF</title><description>The present invention relates to a novel method for obtaining (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-amino] propanoyl] octahydro cyclopenta[b] pyrrole-2-carboxylic acid, viz. Ramipril(I) in high optical purity, free of other stereoisomers, and in high bulk density. The present invention also relates to a novel hydrated form of Ramipril(I) and a process for preparation thereof.
L'invention concerne un procédé d'élaboration d'acide (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(éthoxycarbonyle)-3-phénylpropyle]-amino] propanoyle] octahydro cyclopenta[b] pyrrole-2-carboxylique, à savoir Ramipril(I), de pureté optique élevée, sans autres stéréoisomères, et de poids volumétrique élevé. L'invention concerne également une forme hydratée de Ramipril(I) et un procédé d'élaboration correspondant.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgKCPJ3dg0OVnDzD1JwDooMDnH08fGMcgzx9PdT8HdTCHL09QwI8vRRcPRzUQgIcg1wDILLOSp4RLoAua4uIN2-CiEerkGu_m48DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IwMDUwMzCxMjI0diYOFUAoxIwkg</recordid><startdate>20060119</startdate><enddate>20060119</enddate><creator>SINGH, GIRIJ, PAL</creator><creator>RANANAWARE, UMESH, BABANRAO</creator><creator>DHAKE, VILAS, NATHU</creator><scope>EVB</scope></search><sort><creationdate>20060119</creationdate><title>PROCESS FOR CRYSTALLIZATION OF RAMIPRIL AND PREPARATION OF A HYDRATED FORM THEREOF</title><author>SINGH, GIRIJ, PAL ; RANANAWARE, UMESH, BABANRAO ; DHAKE, VILAS, NATHU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2005068422A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2006</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>SINGH, GIRIJ, PAL</creatorcontrib><creatorcontrib>RANANAWARE, UMESH, BABANRAO</creatorcontrib><creatorcontrib>DHAKE, VILAS, NATHU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SINGH, GIRIJ, PAL</au><au>RANANAWARE, UMESH, BABANRAO</au><au>DHAKE, VILAS, NATHU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR CRYSTALLIZATION OF RAMIPRIL AND PREPARATION OF A HYDRATED FORM THEREOF</title><date>2006-01-19</date><risdate>2006</risdate><abstract>The present invention relates to a novel method for obtaining (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-amino] propanoyl] octahydro cyclopenta[b] pyrrole-2-carboxylic acid, viz. Ramipril(I) in high optical purity, free of other stereoisomers, and in high bulk density. The present invention also relates to a novel hydrated form of Ramipril(I) and a process for preparation thereof.
L'invention concerne un procédé d'élaboration d'acide (2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(éthoxycarbonyle)-3-phénylpropyle]-amino] propanoyle] octahydro cyclopenta[b] pyrrole-2-carboxylique, à savoir Ramipril(I), de pureté optique élevée, sans autres stéréoisomères, et de poids volumétrique élevé. L'invention concerne également une forme hydratée de Ramipril(I) et un procédé d'élaboration correspondant.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2005068422A3 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | PROCESS FOR CRYSTALLIZATION OF RAMIPRIL AND PREPARATION OF A HYDRATED FORM THEREOF |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T06%3A48%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SINGH,%20GIRIJ,%20PAL&rft.date=2006-01-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2005068422A3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |