DOPAMINE UPTAKE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISEASE
Treatment of diseases and disorders related to altered neuronal excitability, especially migraine prophylaxis, mood stabilisation and convulsions, in particular the treatment of convulsions due to epilepsy, also treatment of depression or psychomotor retardation in subjects prone to seizures. Dopami...
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| creator | RICHARDS, FRANCES, MARGARET GOLDSMITH, PAUL HAYES, ANN, GAIL JONES, DEREK, THOMAS, EDWARD |
| description | Treatment of diseases and disorders related to altered neuronal excitability, especially migraine prophylaxis, mood stabilisation and convulsions, in particular the treatment of convulsions due to epilepsy, also treatment of depression or psychomotor retardation in subjects prone to seizures. Dopamine uptake inhibitors are employed, especially benzhydryloxy-ethyl piperazine derivatives, including GBR12909, GBR12935, GBR13069, GBR13098, GBR13119 and pharmaceutically acceptable salts thereof.
Cette invention se rapporte au traitement des maladies et des troubles associés à une excitabilité neuronale altérée, en particulier à la prophylaxie de la migraine, à la stabilisation de l'humeur et au traitement des convulsions, notamment des convulsions dues à l'épilepsie, ainsi qu'au traitement de la dépression et des retards psychomoteurs chez des personnes sujettes aux crises. On utilise à cet effet des inhibiteurs d'absorption de la dopamine, notamment des dérivés de benzhydryloxy-éthyle pipérazine, y compris GBR12909, GBR12935, GBR13069, GBR13098, GBR13119 et des sels de ces composés acceptables sur le plan pharmaceutique. |
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Cette invention se rapporte au traitement des maladies et des troubles associés à une excitabilité neuronale altérée, en particulier à la prophylaxie de la migraine, à la stabilisation de l'humeur et au traitement des convulsions, notamment des convulsions dues à l'épilepsie, ainsi qu'au traitement de la dépression et des retards psychomoteurs chez des personnes sujettes aux crises. On utilise à cet effet des inhibiteurs d'absorption de la dopamine, notamment des dérivés de benzhydryloxy-éthyle pipérazine, y compris GBR12909, GBR12935, GBR13069, GBR13098, GBR13119 et des sels de ces composés acceptables sur le plan pharmaceutique.</description><edition>7</edition><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050915&DB=EPODOC&CC=WO&NR=2005067931A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050915&DB=EPODOC&CC=WO&NR=2005067931A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RICHARDS, FRANCES, MARGARET</creatorcontrib><creatorcontrib>GOLDSMITH, PAUL</creatorcontrib><creatorcontrib>HAYES, ANN, GAIL</creatorcontrib><creatorcontrib>JONES, DEREK, THOMAS, EDWARD</creatorcontrib><title>DOPAMINE UPTAKE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISEASE</title><description>Treatment of diseases and disorders related to altered neuronal excitability, especially migraine prophylaxis, mood stabilisation and convulsions, in particular the treatment of convulsions due to epilepsy, also treatment of depression or psychomotor retardation in subjects prone to seizures. Dopamine uptake inhibitors are employed, especially benzhydryloxy-ethyl piperazine derivatives, including GBR12909, GBR12935, GBR13069, GBR13098, GBR13119 and pharmaceutically acceptable salts thereof.
Cette invention se rapporte au traitement des maladies et des troubles associés à une excitabilité neuronale altérée, en particulier à la prophylaxie de la migraine, à la stabilisation de l'humeur et au traitement des convulsions, notamment des convulsions dues à l'épilepsie, ainsi qu'au traitement de la dépression et des retards psychomoteurs chez des personnes sujettes aux crises. On utilise à cet effet des inhibiteurs d'absorption de la dopamine, notamment des dérivés de benzhydryloxy-éthyle pipérazine, y compris GBR12909, GBR12935, GBR13069, GBR13098, GBR13119 et des sels de ces composés acceptables sur le plan pharmaceutique.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBx8Q9w9PX0c1UIDQhx9HZV8PTz8HTyDPEPClZw8w9SCPFwVQgJcnUM8XX1C1Hwd1Pwcw0N8vfxd_d0dvRRcPEMdnUMduVhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGBqYGZuaWxoaOxsbEqQIAEYosxg</recordid><startdate>20050915</startdate><enddate>20050915</enddate><creator>RICHARDS, FRANCES, MARGARET</creator><creator>GOLDSMITH, PAUL</creator><creator>HAYES, ANN, GAIL</creator><creator>JONES, DEREK, THOMAS, EDWARD</creator><scope>EVB</scope></search><sort><creationdate>20050915</creationdate><title>DOPAMINE UPTAKE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISEASE</title><author>RICHARDS, FRANCES, MARGARET ; GOLDSMITH, PAUL ; HAYES, ANN, GAIL ; JONES, DEREK, THOMAS, EDWARD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2005067931A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2005</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>RICHARDS, FRANCES, MARGARET</creatorcontrib><creatorcontrib>GOLDSMITH, PAUL</creatorcontrib><creatorcontrib>HAYES, ANN, GAIL</creatorcontrib><creatorcontrib>JONES, DEREK, THOMAS, EDWARD</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RICHARDS, FRANCES, MARGARET</au><au>GOLDSMITH, PAUL</au><au>HAYES, ANN, GAIL</au><au>JONES, DEREK, THOMAS, EDWARD</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DOPAMINE UPTAKE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISEASE</title><date>2005-09-15</date><risdate>2005</risdate><abstract>Treatment of diseases and disorders related to altered neuronal excitability, especially migraine prophylaxis, mood stabilisation and convulsions, in particular the treatment of convulsions due to epilepsy, also treatment of depression or psychomotor retardation in subjects prone to seizures. Dopamine uptake inhibitors are employed, especially benzhydryloxy-ethyl piperazine derivatives, including GBR12909, GBR12935, GBR13069, GBR13098, GBR13119 and pharmaceutically acceptable salts thereof.
Cette invention se rapporte au traitement des maladies et des troubles associés à une excitabilité neuronale altérée, en particulier à la prophylaxie de la migraine, à la stabilisation de l'humeur et au traitement des convulsions, notamment des convulsions dues à l'épilepsie, ainsi qu'au traitement de la dépression et des retards psychomoteurs chez des personnes sujettes aux crises. On utilise à cet effet des inhibiteurs d'absorption de la dopamine, notamment des dérivés de benzhydryloxy-éthyle pipérazine, y compris GBR12909, GBR12935, GBR13069, GBR13098, GBR13119 et des sels de ces composés acceptables sur le plan pharmaceutique.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| title | DOPAMINE UPTAKE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISEASE |
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