METHODS FOR THE IN VITRO DIAGNOSIS AND IN VITRO PROGNOSIS OF CANCER OF THE PANCREAS AND FOR THE DEVELOPMENT OF DRUGS AGAINST CANCER OF THE PANCREAS AND/OR PANCREATITIS
The present invention refers to an in vitro method to detect pancreatic ductal adenocarcinoma and/or pancreatitis in an individual, to determine the stage or severity of said conditions in an individual, or to monitor the effect of therapy administeied to an individual with either one or both of sai...
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| creator | ARGUEELLES SANCHEZ, MARIA, ELADIA DEL AMO IRIBARREN, JOKIN ARIZ LOPEZ DE CASTRO, USUE OCHOA GARAY, JORGE ESCUDERO GARCIA DE GALDEANO, PEDRO JUNQUERA SANCHEZ-VALLEJO, CORINA DE LOS TOYOS GONZALEZ, JUAN RAMON SANTA CRUZ, SIMON BARNEO SERRA, LUIS SIMON BUELA, LAUREANO MARTINEZ MARTINEZ, ANTONIO |
| description | The present invention refers to an in vitro method to detect pancreatic ductal adenocarcinoma and/or pancreatitis in an individual, to determine the stage or severity of said conditions in an individual, or to monitor the effect of therapy administeied to an individual with either one or both of said conditions; to screen for, identify, develop and evaluate the efficacy of compounds for the treatment of said conditions of the pancreas aimed at developing new medicinal products, as well as agents that inhibit the expression and/or activity of the DRM protein and/or the NBL1 protein, and/or the effects of said expression.
La présente invention se rapporte à une méthode in vitro permettant de détecter un adénocarcinome du canal pancréatique et/ou une pancréatite chez un individu, de déterminer le stade ou la gravité de ces affections chez un individu, ou de surveiller l'effet d'un traitement administré à un individu présentant l'une ou l'autre de ces affections, et de rechercher par criblage, d'identifier et de mettre au point des composés pour le traitement de ces affections du pancréas et d'en évaluer l'efficacité en vue de la mise au point de nouveaux produits médicaux. L'invention concerne également des agents inhibant l'expression et/ou l'activité de la protéine DRM et/ou de la protéine NBL1, et/ou les effets de cette expression. |
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La présente invention se rapporte à une méthode in vitro permettant de détecter un adénocarcinome du canal pancréatique et/ou une pancréatite chez un individu, de déterminer le stade ou la gravité de ces affections chez un individu, ou de surveiller l'effet d'un traitement administré à un individu présentant l'une ou l'autre de ces affections, et de rechercher par criblage, d'identifier et de mettre au point des composés pour le traitement de ces affections du pancréas et d'en évaluer l'efficacité en vue de la mise au point de nouveaux produits médicaux. L'invention concerne également des agents inhibant l'expression et/ou l'activité de la protéine DRM et/ou de la protéine NBL1, et/ou les effets de cette expression.</description><edition>7</edition><language>eng ; fre</language><subject>CHEMISTRY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; TESTING</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050331&DB=EPODOC&CC=WO&NR=2005029082A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050331&DB=EPODOC&CC=WO&NR=2005029082A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ARGUEELLES SANCHEZ, MARIA, ELADIA</creatorcontrib><creatorcontrib>DEL AMO IRIBARREN, JOKIN</creatorcontrib><creatorcontrib>ARIZ LOPEZ DE CASTRO, USUE</creatorcontrib><creatorcontrib>OCHOA GARAY, JORGE</creatorcontrib><creatorcontrib>ESCUDERO GARCIA DE GALDEANO, PEDRO</creatorcontrib><creatorcontrib>JUNQUERA SANCHEZ-VALLEJO, CORINA</creatorcontrib><creatorcontrib>DE LOS TOYOS GONZALEZ, JUAN RAMON</creatorcontrib><creatorcontrib>SANTA CRUZ, SIMON</creatorcontrib><creatorcontrib>BARNEO SERRA, LUIS</creatorcontrib><creatorcontrib>SIMON BUELA, LAUREANO</creatorcontrib><creatorcontrib>MARTINEZ MARTINEZ, ANTONIO</creatorcontrib><title>METHODS FOR THE IN VITRO DIAGNOSIS AND IN VITRO PROGNOSIS OF CANCER OF THE PANCREAS AND FOR THE DEVELOPMENT OF DRUGS AGAINST CANCER OF THE PANCREAS AND/OR PANCREATITIS</title><description>The present invention refers to an in vitro method to detect pancreatic ductal adenocarcinoma and/or pancreatitis in an individual, to determine the stage or severity of said conditions in an individual, or to monitor the effect of therapy administeied to an individual with either one or both of said conditions; to screen for, identify, develop and evaluate the efficacy of compounds for the treatment of said conditions of the pancreas aimed at developing new medicinal products, as well as agents that inhibit the expression and/or activity of the DRM protein and/or the NBL1 protein, and/or the effects of said expression.
La présente invention se rapporte à une méthode in vitro permettant de détecter un adénocarcinome du canal pancréatique et/ou une pancréatite chez un individu, de déterminer le stade ou la gravité de ces affections chez un individu, ou de surveiller l'effet d'un traitement administré à un individu présentant l'une ou l'autre de ces affections, et de rechercher par criblage, d'identifier et de mettre au point des composés pour le traitement de ces affections du pancréas et d'en évaluer l'efficacité en vue de la mise au point de nouveaux produits médicaux. L'invention concerne également des agents inhibant l'expression et/ou l'activité de la protéine DRM et/ou de la protéine NBL1, et/ou les effets de cette expression.</description><subject>CHEMISTRY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQRbtxIeodBlyLISLoMjTTNGAzJRnrshSJK9FCvZPXtMWKO3E1_3_em2nyLJBz0gEy8sA5gnVQWfYE2irjKNgAyunvXHoaZ8ogVS5FP6RBLfvmUb2Fzz-NFR6oLNDxwGl_ND1glHWBf_jrXh87W7ZhnkwuzbWLi_HOkmWGnOar2N7r2LXNOd7ioz6RFGIr5F7spJKb_6gX4NJG3g</recordid><startdate>20050331</startdate><enddate>20050331</enddate><creator>ARGUEELLES SANCHEZ, MARIA, ELADIA</creator><creator>DEL AMO IRIBARREN, JOKIN</creator><creator>ARIZ LOPEZ DE CASTRO, USUE</creator><creator>OCHOA GARAY, JORGE</creator><creator>ESCUDERO GARCIA DE GALDEANO, PEDRO</creator><creator>JUNQUERA SANCHEZ-VALLEJO, CORINA</creator><creator>DE LOS TOYOS GONZALEZ, JUAN RAMON</creator><creator>SANTA CRUZ, SIMON</creator><creator>BARNEO SERRA, LUIS</creator><creator>SIMON BUELA, LAUREANO</creator><creator>MARTINEZ MARTINEZ, ANTONIO</creator><scope>EVB</scope></search><sort><creationdate>20050331</creationdate><title>METHODS FOR THE IN VITRO DIAGNOSIS AND IN VITRO PROGNOSIS OF CANCER OF THE PANCREAS AND FOR THE DEVELOPMENT OF DRUGS AGAINST CANCER OF THE PANCREAS AND/OR PANCREATITIS</title><author>ARGUEELLES SANCHEZ, MARIA, ELADIA ; DEL AMO IRIBARREN, JOKIN ; ARIZ LOPEZ DE CASTRO, USUE ; OCHOA GARAY, JORGE ; ESCUDERO GARCIA DE GALDEANO, PEDRO ; JUNQUERA SANCHEZ-VALLEJO, CORINA ; DE LOS TOYOS GONZALEZ, JUAN RAMON ; SANTA CRUZ, SIMON ; BARNEO SERRA, LUIS ; SIMON BUELA, LAUREANO ; MARTINEZ MARTINEZ, ANTONIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2005029082A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2005</creationdate><topic>CHEMISTRY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>ARGUEELLES SANCHEZ, MARIA, ELADIA</creatorcontrib><creatorcontrib>DEL AMO IRIBARREN, JOKIN</creatorcontrib><creatorcontrib>ARIZ LOPEZ DE CASTRO, USUE</creatorcontrib><creatorcontrib>OCHOA GARAY, JORGE</creatorcontrib><creatorcontrib>ESCUDERO GARCIA DE GALDEANO, PEDRO</creatorcontrib><creatorcontrib>JUNQUERA SANCHEZ-VALLEJO, CORINA</creatorcontrib><creatorcontrib>DE LOS TOYOS GONZALEZ, JUAN RAMON</creatorcontrib><creatorcontrib>SANTA CRUZ, SIMON</creatorcontrib><creatorcontrib>BARNEO SERRA, LUIS</creatorcontrib><creatorcontrib>SIMON BUELA, LAUREANO</creatorcontrib><creatorcontrib>MARTINEZ MARTINEZ, ANTONIO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ARGUEELLES SANCHEZ, MARIA, ELADIA</au><au>DEL AMO IRIBARREN, JOKIN</au><au>ARIZ LOPEZ DE CASTRO, USUE</au><au>OCHOA GARAY, JORGE</au><au>ESCUDERO GARCIA DE GALDEANO, PEDRO</au><au>JUNQUERA SANCHEZ-VALLEJO, CORINA</au><au>DE LOS TOYOS GONZALEZ, JUAN RAMON</au><au>SANTA CRUZ, SIMON</au><au>BARNEO SERRA, LUIS</au><au>SIMON BUELA, LAUREANO</au><au>MARTINEZ MARTINEZ, ANTONIO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS FOR THE IN VITRO DIAGNOSIS AND IN VITRO PROGNOSIS OF CANCER OF THE PANCREAS AND FOR THE DEVELOPMENT OF DRUGS AGAINST CANCER OF THE PANCREAS AND/OR PANCREATITIS</title><date>2005-03-31</date><risdate>2005</risdate><abstract>The present invention refers to an in vitro method to detect pancreatic ductal adenocarcinoma and/or pancreatitis in an individual, to determine the stage or severity of said conditions in an individual, or to monitor the effect of therapy administeied to an individual with either one or both of said conditions; to screen for, identify, develop and evaluate the efficacy of compounds for the treatment of said conditions of the pancreas aimed at developing new medicinal products, as well as agents that inhibit the expression and/or activity of the DRM protein and/or the NBL1 protein, and/or the effects of said expression.
La présente invention se rapporte à une méthode in vitro permettant de détecter un adénocarcinome du canal pancréatique et/ou une pancréatite chez un individu, de déterminer le stade ou la gravité de ces affections chez un individu, ou de surveiller l'effet d'un traitement administré à un individu présentant l'une ou l'autre de ces affections, et de rechercher par criblage, d'identifier et de mettre au point des composés pour le traitement de ces affections du pancréas et d'en évaluer l'efficacité en vue de la mise au point de nouveaux produits médicaux. L'invention concerne également des agents inhibant l'expression et/ou l'activité de la protéine DRM et/ou de la protéine NBL1, et/ou les effets de cette expression.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS TESTING |
| title | METHODS FOR THE IN VITRO DIAGNOSIS AND IN VITRO PROGNOSIS OF CANCER OF THE PANCREAS AND FOR THE DEVELOPMENT OF DRUGS AGAINST CANCER OF THE PANCREAS AND/OR PANCREATITIS |
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