MPTENS AS MODIFIERS OF THE PTEN PATHWAY AND METHODS OF USE
Human MPTEN genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of MPTEN are provided. Selon la présente...
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| creator | LICKTEIG, KIM COSTA, MICHAEL, R BJERKE, LYNN, MARGARET MCGRATH, GARTH, JOSEPH |
| description | Human MPTEN genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of MPTEN are provided.
Selon la présente invention, des gènes MPTEN humains ont été identifiés comme modulateurs de la voie PTEN, et constituent par conséquent des cibles thérapeutiques dans les troubles associés à un fonctionnement défectueux de PTEN. L'invention porte sur des procédés permettant d'identifier des modulateurs de PTEN, selon lesquels on procède à un criblage d'agents qui modulent l'activité de MPTEN. |
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Selon la présente invention, des gènes MPTEN humains ont été identifiés comme modulateurs de la voie PTEN, et constituent par conséquent des cibles thérapeutiques dans les troubles associés à un fonctionnement défectueux de PTEN. L'invention porte sur des procédés permettant d'identifier des modulateurs de PTEN, selon lesquels on procède à un criblage d'agents qui modulent l'activité de MPTEN.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060601&DB=EPODOC&CC=WO&NR=2005017123A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060601&DB=EPODOC&CC=WO&NR=2005017123A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LICKTEIG, KIM</creatorcontrib><creatorcontrib>COSTA, MICHAEL, R</creatorcontrib><creatorcontrib>BJERKE, LYNN, MARGARET</creatorcontrib><creatorcontrib>MCGRATH, GARTH, JOSEPH</creatorcontrib><title>MPTENS AS MODIFIERS OF THE PTEN PATHWAY AND METHODS OF USE</title><description>Human MPTEN genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of MPTEN are provided.
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
| title | MPTENS AS MODIFIERS OF THE PTEN PATHWAY AND METHODS OF USE |
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