CILIARY NEUROTROPHIC FACTOR VARIANTS

The present invention relates to variant ciliary neurotrophic factor (CNTF) proteins that possess neuroprotective and/or weight loss activity and reduced immunogenicity. In particular, variants of CNTF with reduced ability to bind one or more human class II MHC molecules are described. L'invent...

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Hauptverfasser: BARBOSA, MARIA, D.F.S, MARSHALL, SHANNON, ALICIA
Format: Patent
Sprache:eng ; fre
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