CONJUGATED LINOLENIC ACIDS AND METHODS OF PREPARATION AND PURIFICATION AND USES THEREOF

This invention relates to a new conjugated linoleic acids, a process for preparation thereof and method of use. Thus this invention is concerned with the preparation and purification of conjugated linoleic acids from materials rich in alpha or gamma linoleic acids. The reaction produces a mixture co...

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Hauptverfasser: BRIAND, SANDIE, GARRO GALVEZ, JUAN-MIGUEL, ANGERS, PAUL
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GARRO GALVEZ, JUAN-MIGUEL
ANGERS, PAUL
description This invention relates to a new conjugated linoleic acids, a process for preparation thereof and method of use. Thus this invention is concerned with the preparation and purification of conjugated linoleic acids from materials rich in alpha or gamma linoleic acids. The reaction produces a mixture containing a 1:1 ratio of 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15Z-octadecatrieonic acid. The mixture can be purified up to 90 % by liquid chromatography, crystallization or urea crystallization. The mixture of 1:1 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15E, 15Z-octadecatrienoic acid have anticancerous activities. L'invention concerne des nouveaux acides linoléniques conjugués, un procédé de préparation de ceux-ci et un procédé d'utilisation de ceux-ci. L'invention concerne également la préparation et la purification d'acides linoléniques conjugués à partir de matériaux riches en acides alpha-linoléniques et en acides gamma-linoléniques. La réaction produit un mélange contenant un rapport de 1:1 d'acide 9Z, 11E, 15Z-octadécatriénoïque et d'acide 9Z, 13E, 15Z-octadécatriénoïque. Ce mélange peut être purifié jusqu'à 90 % par chromatographie en phase liquide, par cristallisation ou par cristallisation de l'urée. Ledit mélange contenant un rapport de 1:1 d'acide 9Z, 11E, 15Z-octadécatriénoïque et d'acide 9Z, 13E, 15Z-octadécatriénoïque présente des activités anticancéreuses.
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Thus this invention is concerned with the preparation and purification of conjugated linoleic acids from materials rich in alpha or gamma linoleic acids. The reaction produces a mixture containing a 1:1 ratio of 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15Z-octadecatrieonic acid. The mixture can be purified up to 90 % by liquid chromatography, crystallization or urea crystallization. The mixture of 1:1 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15E, 15Z-octadecatrienoic acid have anticancerous activities. L'invention concerne des nouveaux acides linoléniques conjugués, un procédé de préparation de ceux-ci et un procédé d'utilisation de ceux-ci. L'invention concerne également la préparation et la purification d'acides linoléniques conjugués à partir de matériaux riches en acides alpha-linoléniques et en acides gamma-linoléniques. La réaction produit un mélange contenant un rapport de 1:1 d'acide 9Z, 11E, 15Z-octadécatriénoïque et d'acide 9Z, 13E, 15Z-octadécatriénoïque. 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Thus this invention is concerned with the preparation and purification of conjugated linoleic acids from materials rich in alpha or gamma linoleic acids. The reaction produces a mixture containing a 1:1 ratio of 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15Z-octadecatrieonic acid. The mixture can be purified up to 90 % by liquid chromatography, crystallization or urea crystallization. The mixture of 1:1 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15E, 15Z-octadecatrienoic acid have anticancerous activities. L'invention concerne des nouveaux acides linoléniques conjugués, un procédé de préparation de ceux-ci et un procédé d'utilisation de ceux-ci. L'invention concerne également la préparation et la purification d'acides linoléniques conjugués à partir de matériaux riches en acides alpha-linoléniques et en acides gamma-linoléniques. La réaction produit un mélange contenant un rapport de 1:1 d'acide 9Z, 11E, 15Z-octadécatriénoïque et d'acide 9Z, 13E, 15Z-octadécatriénoïque. 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Thus this invention is concerned with the preparation and purification of conjugated linoleic acids from materials rich in alpha or gamma linoleic acids. The reaction produces a mixture containing a 1:1 ratio of 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15Z-octadecatrieonic acid. The mixture can be purified up to 90 % by liquid chromatography, crystallization or urea crystallization. The mixture of 1:1 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15E, 15Z-octadecatrienoic acid have anticancerous activities. L'invention concerne des nouveaux acides linoléniques conjugués, un procédé de préparation de ceux-ci et un procédé d'utilisation de ceux-ci. L'invention concerne également la préparation et la purification d'acides linoléniques conjugués à partir de matériaux riches en acides alpha-linoléniques et en acides gamma-linoléniques. La réaction produit un mélange contenant un rapport de 1:1 d'acide 9Z, 11E, 15Z-octadécatriénoïque et d'acide 9Z, 13E, 15Z-octadécatriénoïque. Ce mélange peut être purifié jusqu'à 90 % par chromatographie en phase liquide, par cristallisation ou par cristallisation de l'urée. Ledit mélange contenant un rapport de 1:1 d'acide 9Z, 11E, 15Z-octadécatriénoïque et d'acide 9Z, 13E, 15Z-octadécatriénoïque présente des activités anticancéreuses.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES
CANDLES
CHEMISTRY
DETERGENTS
EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKINGOILS
ESSENTIAL OILS
FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS,OILS, OR FATTY ACIDS OBTAINED THEREFROM
FATTY ACIDS FROM FATS, OILS OR WAXES
FATTY ACIDS THEREFROM
FODDER
FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PERFUMES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
PRODUCING (PRESSING, EXTRACTION), REFINING AND PRESERVINGFATS, FATTY SUBSTANCES (e.g. LANOLIN), FATTY OILS AND WAXES,INCLUDING EXTRACTION FROM WASTE MATERIALS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title CONJUGATED LINOLENIC ACIDS AND METHODS OF PREPARATION AND PURIFICATION AND USES THEREOF
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