TUMOUR NECROSIS FACTOR RECEPTOR MOLECULES WITH REDUCED IMMUNOGENICITY

The invention relates to the modification of human soluble tumor necrosis factor receptor type 1 (sTNFR1) to result in sTNFR1 proteins, preferably fusion proteins comprising an immunoglobulin heavy chain constant region (Fc domain) and modified human sTNFR-I. These molecules are substantially non-im...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	BAKER, MATTHEW, HELLENDOORN, KOEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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