METHOD AND COMPOSITIONS FOR MODULATING AMYLOID PRECURSOR PROTEIN TRANSLATION
The invention relates to products and methods for modulating amyloid precursor protein (APP) translation and/or amyloid ß(Aß) secretion. The methods of the invention are useful to prevent and treat APP translation and/or Aß secretion-associated neurological disorders such as Alzheimer's disease...
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| creator | ROGERS, JACK RANDALL, JEFF SARANG, SATINDER GULLANS, STEVE PAYTON, SANDRA |
| description | The invention relates to products and methods for modulating amyloid precursor protein (APP) translation and/or amyloid ß(Aß) secretion. The methods of the invention are useful to prevent and treat APP translation and/or Aß secretion-associated neurological disorders such as Alzheimer's disease, Down's syndrome, cerebrovascular amyloidosis, Hereditary Amyloidosis with Cerebral Hemorrhage of the Dutch Type, vascular dementia, and inclusion body myositis.
L'invention concerne des produits et des procédés permettant de moduler la traduction de la protéine précurseur amyloïde (APP) et/ou la sécrétion de protéine beta -amyloïde. Les procédés de l'invention sont utiles pour prévenir et traiter des troubles neurologiques associés à la traduction d'APP et/ou à la sécrétion de protéine beta -amyloïde tels que la maladie d'Alzheimer, le syndrome de Down, l'amylose cérébrovasculaire, l'amylose héréditaire avec hémorragie cérébrale de type hollandais, la démence vasculaire et la myosite à inclusions. |
| format | Patent |
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L'invention concerne des produits et des procédés permettant de moduler la traduction de la protéine précurseur amyloïde (APP) et/ou la sécrétion de protéine beta -amyloïde. Les procédés de l'invention sont utiles pour prévenir et traiter des troubles neurologiques associés à la traduction d'APP et/ou à la sécrétion de protéine beta -amyloïde tels que la maladie d'Alzheimer, le syndrome de Down, l'amylose cérébrovasculaire, l'amylose héréditaire avec hémorragie cérébrale de type hollandais, la démence vasculaire et la myosite à inclusions.</description><edition>7</edition><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20041229&DB=EPODOC&CC=WO&NR=2004112700A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20041229&DB=EPODOC&CC=WO&NR=2004112700A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROGERS, JACK</creatorcontrib><creatorcontrib>RANDALL, JEFF</creatorcontrib><creatorcontrib>SARANG, SATINDER</creatorcontrib><creatorcontrib>GULLANS, STEVE</creatorcontrib><creatorcontrib>PAYTON, SANDRA</creatorcontrib><title>METHOD AND COMPOSITIONS FOR MODULATING AMYLOID PRECURSOR PROTEIN TRANSLATION</title><description>The invention relates to products and methods for modulating amyloid precursor protein (APP) translation and/or amyloid ß(Aß) secretion. The methods of the invention are useful to prevent and treat APP translation and/or Aß secretion-associated neurological disorders such as Alzheimer's disease, Down's syndrome, cerebrovascular amyloidosis, Hereditary Amyloidosis with Cerebral Hemorrhage of the Dutch Type, vascular dementia, and inclusion body myositis.
L'invention concerne des produits et des procédés permettant de moduler la traduction de la protéine précurseur amyloïde (APP) et/ou la sécrétion de protéine beta -amyloïde. Les procédés de l'invention sont utiles pour prévenir et traiter des troubles neurologiques associés à la traduction d'APP et/ou à la sécrétion de protéine beta -amyloïde tels que la maladie d'Alzheimer, le syndrome de Down, l'amylose cérébrovasculaire, l'amylose héréditaire avec hémorragie cérébrale de type hollandais, la démence vasculaire et la myosite à inclusions.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEsDqK-w4GzkEbBOSSpDSR3IbkiTqVInEQL9f1RwQdw-of_W4oQHXdkQaMFQzFR8ewJC7SUIZLtg2aPJ9DxEshbSNmZPpfPTJnYeQTOGstXEa7F4jbe57r5dSW2rWPT7er0HOo8jdf6qK_hTErKQ9Ooo5Ra7f9Tb7Z0L2E</recordid><startdate>20041229</startdate><enddate>20041229</enddate><creator>ROGERS, JACK</creator><creator>RANDALL, JEFF</creator><creator>SARANG, SATINDER</creator><creator>GULLANS, STEVE</creator><creator>PAYTON, SANDRA</creator><scope>EVB</scope></search><sort><creationdate>20041229</creationdate><title>METHOD AND COMPOSITIONS FOR MODULATING AMYLOID PRECURSOR PROTEIN TRANSLATION</title><author>ROGERS, JACK ; RANDALL, JEFF ; SARANG, SATINDER ; GULLANS, STEVE ; PAYTON, SANDRA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2004112700A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2004</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>ROGERS, JACK</creatorcontrib><creatorcontrib>RANDALL, JEFF</creatorcontrib><creatorcontrib>SARANG, SATINDER</creatorcontrib><creatorcontrib>GULLANS, STEVE</creatorcontrib><creatorcontrib>PAYTON, SANDRA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROGERS, JACK</au><au>RANDALL, JEFF</au><au>SARANG, SATINDER</au><au>GULLANS, STEVE</au><au>PAYTON, SANDRA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD AND COMPOSITIONS FOR MODULATING AMYLOID PRECURSOR PROTEIN TRANSLATION</title><date>2004-12-29</date><risdate>2004</risdate><abstract>The invention relates to products and methods for modulating amyloid precursor protein (APP) translation and/or amyloid ß(Aß) secretion. The methods of the invention are useful to prevent and treat APP translation and/or Aß secretion-associated neurological disorders such as Alzheimer's disease, Down's syndrome, cerebrovascular amyloidosis, Hereditary Amyloidosis with Cerebral Hemorrhage of the Dutch Type, vascular dementia, and inclusion body myositis.
L'invention concerne des produits et des procédés permettant de moduler la traduction de la protéine précurseur amyloïde (APP) et/ou la sécrétion de protéine beta -amyloïde. Les procédés de l'invention sont utiles pour prévenir et traiter des troubles neurologiques associés à la traduction d'APP et/ou à la sécrétion de protéine beta -amyloïde tels que la maladie d'Alzheimer, le syndrome de Down, l'amylose cérébrovasculaire, l'amylose héréditaire avec hémorragie cérébrale de type hollandais, la démence vasculaire et la myosite à inclusions.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
| title | METHOD AND COMPOSITIONS FOR MODULATING AMYLOID PRECURSOR PROTEIN TRANSLATION |
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