PURIFICATION OF BIOLOGICALLY-PRODUCED 1,3-PROPANEDIOL

A process for purifying 1,3-propanediol from the fermentation broth of a cultured E. coli that has been bioengineered to synthesize 1,3-propanediol from sugar is provided. The basic process entails filtration, ion exchange and distillation of the fermentation broth product stream, preferably includi...

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Hauptverfasser: FITZGIBBON, PATRICK, WENNDT, GREGORY, M, TROTTER, ROBERT, E, LEHNHARDT, WILLIAM, F, DISNEY, JAMES, M, GALLAGHER, F., GLENN, DRAVIS, BRYAN, C, CHU, LUIS, ALBERTO, GADDY, JAMES, M, SEAPAN, MAYIS, ADKESSON, DENNIS, MICHAEL, AMES, TYLER, T, YU, EUGENE, K, LUYBEN, MICHAEL, L, LIEVENSE, JEFFERSON, C, ALSOP, ALBERT, W
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creator FITZGIBBON, PATRICK
WENNDT, GREGORY, M
TROTTER, ROBERT, E
LEHNHARDT, WILLIAM, F
DISNEY, JAMES, M
GALLAGHER, F., GLENN
DRAVIS, BRYAN, C
CHU, LUIS, ALBERTO
GADDY, JAMES, M
SEAPAN, MAYIS
ADKESSON, DENNIS, MICHAEL
AMES, TYLER, T
YU, EUGENE, K
LUYBEN, MICHAEL, L
LIEVENSE, JEFFERSON, C
ALSOP, ALBERT, W
description A process for purifying 1,3-propanediol from the fermentation broth of a cultured E. coli that has been bioengineered to synthesize 1,3-propanediol from sugar is provided. The basic process entails filtration, ion exchange and distillation of the fermentation broth product stream, preferably including chemical reduction of the product during the distillation procedure. Also provided are highly purified compositions of 1,3-propanediol. La présente invention concerne un procédé permettant de purifier du 1,3-propanediol issu du bouillon de fermentation d'une culture de E. coli qui a été traité par génie biologique pour synthétiser le 1,3-propanediol à partir du sucre. Le procédé de base fait intervenir une filtration, un échange d'ions et une distillation du diluat du bouillon de fermentation, de préférence avec réduction chimique du produit pendant la distillation. L'invention concerne également des compositions hautement purifiées à base de 1,3-propanediol.
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The basic process entails filtration, ion exchange and distillation of the fermentation broth product stream, preferably including chemical reduction of the product during the distillation procedure. Also provided are highly purified compositions of 1,3-propanediol. La présente invention concerne un procédé permettant de purifier du 1,3-propanediol issu du bouillon de fermentation d'une culture de E. coli qui a été traité par génie biologique pour synthétiser le 1,3-propanediol à partir du sucre. Le procédé de base fait intervenir une filtration, un échange d'ions et une distillation du diluat du bouillon de fermentation, de préférence avec réduction chimique du produit pendant la distillation. 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The basic process entails filtration, ion exchange and distillation of the fermentation broth product stream, preferably including chemical reduction of the product during the distillation procedure. Also provided are highly purified compositions of 1,3-propanediol. La présente invention concerne un procédé permettant de purifier du 1,3-propanediol issu du bouillon de fermentation d'une culture de E. coli qui a été traité par génie biologique pour synthétiser le 1,3-propanediol à partir du sucre. Le procédé de base fait intervenir une filtration, un échange d'ions et une distillation du diluat du bouillon de fermentation, de préférence avec réduction chimique du produit pendant la distillation. L'invention concerne également des compositions hautement purifiées à base de 1,3-propanediol.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
SPIRITS
TRANSPORTING
VINEGAR
WINE
title PURIFICATION OF BIOLOGICALLY-PRODUCED 1,3-PROPANEDIOL
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