REPLICATION ASSAY FOR DISCOVERING ANTIVIRAL SUBSTANCES USING A HIGH THROUGHPUT SCREENING (HTS) METHOD
Die vorliegende Erfindung betrifft ein HTS Testverfahren auf Basis des dem Hepatitis C Virus (HCV) analogen Virus der bovinen viralen Diarrhö (BVDV) in einem in vitro Replikationstest mit infektiösem BVDV auf bovinen Zellen und als Eintopfverfahren. Das Testverfahren eignet sich zur einfachen und sc...
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| creator | PAESSENS, ARNOLD |
| description | Die vorliegende Erfindung betrifft ein HTS Testverfahren auf Basis des dem Hepatitis C Virus (HCV) analogen Virus der bovinen viralen Diarrhö (BVDV) in einem in vitro Replikationstest mit infektiösem BVDV auf bovinen Zellen und als Eintopfverfahren. Das Testverfahren eignet sich zur einfachen und schnellen Testung grosser Substanzbanken hinsichtlich der Auffindung und Charakterisierung neuer Hemmstoffe für Flaviviren.
The invention relates to an high throughput screening (HTS) testing method based on the virus of the bovine viral diarrhea (BVDV), which is analogous to the hepatitis C virus (HCV), in an in-vitro replication test with infectious BVDV on bovine cells and provided in the form of a one-pot method. The test method is suited for the simple and rapid testing of large substance banks with regard to the discovery and characterization of novel inhibitors for flaviruses.
L'invention concerne un procédé d'essai par criblage haute capacité, sur la base du virus de la diarrhée virale bovine (BVD), analogue au virus de l'hépatite C (VHC), dans un test de réplication in vitro avec le virus de la BVD, sur ces cellules bobines, et se présentant sous forme de procédé se déroulant en récipient unique. Ledit procédé d'essai s'utilise pour tester simplement et rapidement des banques importantes de substances, afin de trouver et de caractériser de nouveaux inhibiteurs de flavivirus. |
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The invention relates to an high throughput screening (HTS) testing method based on the virus of the bovine viral diarrhea (BVDV), which is analogous to the hepatitis C virus (HCV), in an in-vitro replication test with infectious BVDV on bovine cells and provided in the form of a one-pot method. The test method is suited for the simple and rapid testing of large substance banks with regard to the discovery and characterization of novel inhibitors for flaviruses.
L'invention concerne un procédé d'essai par criblage haute capacité, sur la base du virus de la diarrhée virale bovine (BVD), analogue au virus de l'hépatite C (VHC), dans un test de réplication in vitro avec le virus de la BVD, sur ces cellules bobines, et se présentant sous forme de procédé se déroulant en récipient unique. Ledit procédé d'essai s'utilise pour tester simplement et rapidement des banques importantes de substances, afin de trouver et de caractériser de nouveaux inhibiteurs de flavivirus.</description><edition>7</edition><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040930&DB=EPODOC&CC=WO&NR=2004083462A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040930&DB=EPODOC&CC=WO&NR=2004083462A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PAESSENS, ARNOLD</creatorcontrib><title>REPLICATION ASSAY FOR DISCOVERING ANTIVIRAL SUBSTANCES USING A HIGH THROUGHPUT SCREENING (HTS) METHOD</title><description>Die vorliegende Erfindung betrifft ein HTS Testverfahren auf Basis des dem Hepatitis C Virus (HCV) analogen Virus der bovinen viralen Diarrhö (BVDV) in einem in vitro Replikationstest mit infektiösem BVDV auf bovinen Zellen und als Eintopfverfahren. Das Testverfahren eignet sich zur einfachen und schnellen Testung grosser Substanzbanken hinsichtlich der Auffindung und Charakterisierung neuer Hemmstoffe für Flaviviren.
The invention relates to an high throughput screening (HTS) testing method based on the virus of the bovine viral diarrhea (BVDV), which is analogous to the hepatitis C virus (HCV), in an in-vitro replication test with infectious BVDV on bovine cells and provided in the form of a one-pot method. The test method is suited for the simple and rapid testing of large substance banks with regard to the discovery and characterization of novel inhibitors for flaviruses.
L'invention concerne un procédé d'essai par criblage haute capacité, sur la base du virus de la diarrhée virale bovine (BVD), analogue au virus de l'hépatite C (VHC), dans un test de réplication in vitro avec le virus de la BVD, sur ces cellules bobines, et se présentant sous forme de procédé se déroulant en récipient unique. Ledit procédé d'essai s'utilise pour tester simplement et rapidement des banques importantes de substances, afin de trouver et de caractériser de nouveaux inhibiteurs de flavivirus.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEuDqK-w4GLDkJpi7jGNO0d1KTkLhWnUiROooX6_ojiAzj9w_fPk-hN25BWQs6CYlYXqJyHkli7zniyNSgr1JFXDXA4siirDUPgLwFSjSDoXaixDQKsvTH2YxsU3sLJCLpymcxuw32Kq18XyboyonEXx2cfp3G4xkd89WeXpWmRHvJin6ks_-96A3sKNdw</recordid><startdate>20040930</startdate><enddate>20040930</enddate><creator>PAESSENS, ARNOLD</creator><scope>EVB</scope></search><sort><creationdate>20040930</creationdate><title>REPLICATION ASSAY FOR DISCOVERING ANTIVIRAL SUBSTANCES USING A HIGH THROUGHPUT SCREENING (HTS) METHOD</title><author>PAESSENS, ARNOLD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2004083462A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2004</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>PAESSENS, ARNOLD</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PAESSENS, ARNOLD</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>REPLICATION ASSAY FOR DISCOVERING ANTIVIRAL SUBSTANCES USING A HIGH THROUGHPUT SCREENING (HTS) METHOD</title><date>2004-09-30</date><risdate>2004</risdate><abstract>Die vorliegende Erfindung betrifft ein HTS Testverfahren auf Basis des dem Hepatitis C Virus (HCV) analogen Virus der bovinen viralen Diarrhö (BVDV) in einem in vitro Replikationstest mit infektiösem BVDV auf bovinen Zellen und als Eintopfverfahren. Das Testverfahren eignet sich zur einfachen und schnellen Testung grosser Substanzbanken hinsichtlich der Auffindung und Charakterisierung neuer Hemmstoffe für Flaviviren.
The invention relates to an high throughput screening (HTS) testing method based on the virus of the bovine viral diarrhea (BVDV), which is analogous to the hepatitis C virus (HCV), in an in-vitro replication test with infectious BVDV on bovine cells and provided in the form of a one-pot method. The test method is suited for the simple and rapid testing of large substance banks with regard to the discovery and characterization of novel inhibitors for flaviruses.
L'invention concerne un procédé d'essai par criblage haute capacité, sur la base du virus de la diarrhée virale bovine (BVD), analogue au virus de l'hépatite C (VHC), dans un test de réplication in vitro avec le virus de la BVD, sur ces cellules bobines, et se présentant sous forme de procédé se déroulant en récipient unique. Ledit procédé d'essai s'utilise pour tester simplement et rapidement des banques importantes de substances, afin de trouver et de caractériser de nouveaux inhibiteurs de flavivirus.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| language | eng ; fre ; ger |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
| title | REPLICATION ASSAY FOR DISCOVERING ANTIVIRAL SUBSTANCES USING A HIGH THROUGHPUT SCREENING (HTS) METHOD |
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