LIGANDS OF ADENINE NUCLEOTIDE TRANSLOCASE (ANT) AND COMPOSITIONS AND METHODS RELATED THERETO
Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Pharmaceutical co...
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| creator | AHLIJANIAN, MICHAEL, K GHOSH, SOUMITRA, S TANG, XIAO-QING LIRAS, SPIROS, J PEI, YAZHONG |
| description | Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.
L'invention concerne des composés présentant une utilité dans le traitement d'états pathologiques associés à une fonction mitochondriale modifiée. Elle concerne notamment des composés de structure (I), y compris des stéréoisomères, des promédicaments et des sels pharmaceutiquement acceptables desdits composés. Dans cette structure, R1, R2, R3, R4, R5 et R6 sont tels que définis dans la description. L'invention concerne en outre des compositions pharmaceutiques contenant un composé de structure (I), ainsi que des méthodes associées à leur utilisation. |
| format | Patent |
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L'invention concerne des composés présentant une utilité dans le traitement d'états pathologiques associés à une fonction mitochondriale modifiée. Elle concerne notamment des composés de structure (I), y compris des stéréoisomères, des promédicaments et des sels pharmaceutiquement acceptables desdits composés. Dans cette structure, R1, R2, R3, R4, R5 et R6 sont tels que définis dans la description. L'invention concerne en outre des compositions pharmaceutiques contenant un composé de structure (I), ainsi que des méthodes associées à leur utilisation.</description><edition>7</edition><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040715&DB=EPODOC&CC=WO&NR=2004058679A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040715&DB=EPODOC&CC=WO&NR=2004058679A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>AHLIJANIAN, MICHAEL, K</creatorcontrib><creatorcontrib>GHOSH, SOUMITRA, S</creatorcontrib><creatorcontrib>TANG, XIAO-QING</creatorcontrib><creatorcontrib>LIRAS, SPIROS, J</creatorcontrib><creatorcontrib>PEI, YAZHONG</creatorcontrib><title>LIGANDS OF ADENINE NUCLEOTIDE TRANSLOCASE (ANT) AND COMPOSITIONS AND METHODS RELATED THERETO</title><description>Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.
L'invention concerne des composés présentant une utilité dans le traitement d'états pathologiques associés à une fonction mitochondriale modifiée. Elle concerne notamment des composés de structure (I), y compris des stéréoisomères, des promédicaments et des sels pharmaceutiquement acceptables desdits composés. Dans cette structure, R1, R2, R3, R4, R5 et R6 sont tels que définis dans la description. L'invention concerne en outre des compositions pharmaceutiques contenant un composé de structure (I), ainsi que des méthodes associées à leur utilisation.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLsKwkAQANNYiPoPCzZaCCG-y-VuYw4uuyG3YiOEIGclGoj_j0H8AKuBYZhxcvXuhGwDSA5oiR0T8Nl4EnWWQGvk4MVgIFgg6xKGGIyUlQSnTjh8RUlayDCpyaOSBS2oJpVpMrq3jz7Ofpwk85zUFKvYvZrYd-0tPuO7uUiWppt0e9jtj5it_6s-U3ozDg</recordid><startdate>20040715</startdate><enddate>20040715</enddate><creator>AHLIJANIAN, MICHAEL, K</creator><creator>GHOSH, SOUMITRA, S</creator><creator>TANG, XIAO-QING</creator><creator>LIRAS, SPIROS, J</creator><creator>PEI, YAZHONG</creator><scope>EVB</scope></search><sort><creationdate>20040715</creationdate><title>LIGANDS OF ADENINE NUCLEOTIDE TRANSLOCASE (ANT) AND COMPOSITIONS AND METHODS RELATED THERETO</title><author>AHLIJANIAN, MICHAEL, K ; GHOSH, SOUMITRA, S ; TANG, XIAO-QING ; LIRAS, SPIROS, J ; PEI, YAZHONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2004058679A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2004</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>AHLIJANIAN, MICHAEL, K</creatorcontrib><creatorcontrib>GHOSH, SOUMITRA, S</creatorcontrib><creatorcontrib>TANG, XIAO-QING</creatorcontrib><creatorcontrib>LIRAS, SPIROS, J</creatorcontrib><creatorcontrib>PEI, YAZHONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>AHLIJANIAN, MICHAEL, K</au><au>GHOSH, SOUMITRA, S</au><au>TANG, XIAO-QING</au><au>LIRAS, SPIROS, J</au><au>PEI, YAZHONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>LIGANDS OF ADENINE NUCLEOTIDE TRANSLOCASE (ANT) AND COMPOSITIONS AND METHODS RELATED THERETO</title><date>2004-07-15</date><risdate>2004</risdate><abstract>Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.
L'invention concerne des composés présentant une utilité dans le traitement d'états pathologiques associés à une fonction mitochondriale modifiée. Elle concerne notamment des composés de structure (I), y compris des stéréoisomères, des promédicaments et des sels pharmaceutiquement acceptables desdits composés. Dans cette structure, R1, R2, R3, R4, R5 et R6 sont tels que définis dans la description. L'invention concerne en outre des compositions pharmaceutiques contenant un composé de structure (I), ainsi que des méthodes associées à leur utilisation.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | LIGANDS OF ADENINE NUCLEOTIDE TRANSLOCASE (ANT) AND COMPOSITIONS AND METHODS RELATED THERETO |
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