HUMAN POLYPEPTIDES ENCODED BY POLYNUCLEOTIDES AND METHODS OF THEIR USE

The invention provides novel polynucleotides, related polypeptides related nucleic acid and polypeptide compositions, and related modulators, such as antibodies and small molecule modulators. The invention also provides methods to make and use these polynucleotides, polypeptides, related composition...

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Hauptverfasser: LINNEMANN, THOMAS, KOTHAKOTA, SRINIVAS, WILLIAMS, LEWIS, T, BEHRENS, DIRK, BEAURANG, PIERRE, ALVARO, ZHANG, HONGBING, CHU, KETING, WU, GE, WANG, YAN, WONG, JUSTIN, G., P, PIERCE, KRISTEN, HESTIR, KEVIN, LEE, ERNESTINE, HAISHAN, LIN, HUANG, MIN, MEI, HALENBECK, ROBERT, FORGAN
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creator LINNEMANN, THOMAS
KOTHAKOTA, SRINIVAS
WILLIAMS, LEWIS, T
BEHRENS, DIRK
BEAURANG, PIERRE, ALVARO
ZHANG, HONGBING
CHU, KETING
WU, GE
WANG, YAN
WONG, JUSTIN, G., P
PIERCE, KRISTEN
HESTIR, KEVIN
LEE, ERNESTINE
HAISHAN, LIN
HUANG, MIN, MEI
HALENBECK, ROBERT, FORGAN
description The invention provides novel polynucleotides, related polypeptides related nucleic acid and polypeptide compositions, and related modulators, such as antibodies and small molecule modulators. The invention also provides methods to make and use these polynucleotides, polypeptides, related compositions, and modulators. These methods include diagnostic, prophylactic and therapeutic applications. The compositions and methods of the invention are useful in treating proliferative disorders, e.g., cancers, and inflammatory, immune, bacterial, and viral disorders. L'invention se rapporte à de nouveaux polynucléotides, à des polypeptides associés, à des compositions de polypeptides et d'acides nucléiques associées, ainsi qu'à des modulateurs associés, tels que des anticorps et à des petites molécules utilisées comme modulateurs. L'invention se rapporte également à des procédés de fabrication et d'utilisation de ces polynucléotides, polypeptides, compositions associées et modulateurs. Lesdits procédés comprennent des applications diagnostiques, prophylactiques et thérapeutiques. Les compositions et les procédés de l'invention sont utiles pour le traitement des troubles prolifératifs, tels que les cancers et les troubles inflammatoires, immuns, bactériens et viraux.
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The invention also provides methods to make and use these polynucleotides, polypeptides, related compositions, and modulators. These methods include diagnostic, prophylactic and therapeutic applications. The compositions and methods of the invention are useful in treating proliferative disorders, e.g., cancers, and inflammatory, immune, bacterial, and viral disorders. L'invention se rapporte à de nouveaux polynucléotides, à des polypeptides associés, à des compositions de polypeptides et d'acides nucléiques associées, ainsi qu'à des modulateurs associés, tels que des anticorps et à des petites molécules utilisées comme modulateurs. L'invention se rapporte également à des procédés de fabrication et d'utilisation de ces polynucléotides, polypeptides, compositions associées et modulateurs. Lesdits procédés comprennent des applications diagnostiques, prophylactiques et thérapeutiques. Les compositions et les procédés de l'invention sont utiles pour le traitement des troubles prolifératifs, tels que les cancers et les troubles inflammatoires, immuns, bactériens et viraux.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title HUMAN POLYPEPTIDES ENCODED BY POLYNUCLEOTIDES AND METHODS OF THEIR USE
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