CELL PENETRATING PEPTIDES

The present invention relates to a method for predicting or designing, detecting, and/or verifying a novel cell-penetrating peptide (CPP) and to a method for using said new CPP and/or a novel usage of a known CPP for an improved cellular uptake of a cellular effector, coupled to said CPP. Furthermor...

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Hauptverfasser:	SOOMETS, URSEL, POOGA, MARGUS, MEIKAS, ANNE, EL-ANDALOUSSI, SAMIR, ELMQUIST, ANNA, METSIS, MADIS, LUNDBERG, PONTUS, ZORKO, MATJAZ, KILK, KALLE, LANGEL, UELO, HAELLBRINK, MATTIAS, LINDGREN, MARIA, OESTENSSON, CLAES, GOERAN, JAERVER, PETER, KOGERMAN, PRIIT, GRAESLUND, ASTRID, SAAR, KUELLIKI, BUDIHNA, METKA, VALKNA, ANDREAS, ERIKSSON, GOERAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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creator	SOOMETS, URSEL POOGA, MARGUS MEIKAS, ANNE EL-ANDALOUSSI, SAMIR ELMQUIST, ANNA METSIS, MADIS LUNDBERG, PONTUS ZORKO, MATJAZ KILK, KALLE LANGEL, UELO HAELLBRINK, MATTIAS LINDGREN, MARIA OESTENSSON, CLAES, GOERAN JAERVER, PETER KOGERMAN, PRIIT GRAESLUND, ASTRID SAAR, KUELLIKI BUDIHNA, METKA VALKNA, ANDREAS ERIKSSON, GOERAN
description	The present invention relates to a method for predicting or designing, detecting, and/or verifying a novel cell-penetrating peptide (CPP) and to a method for using said new CPP and/or a novel usage of a known CPP for an improved cellular uptake of a cellular effector, coupled to said CPP. Furthermore, the present invention also relates to a method for predicting or designing, detecting and/or verifying a novel cell-penetrating peptide (CPP) that mimics cellular effector activity and/or inhibits cellular effector activity. The present invention additionally relates to the use of said CPP for treating and/or preventing a medical condition and to the use of said CPP for the manufacture of a pharmaceutical composition for treating a medical condition. La présente invention concerne un procédé permettant de prédire ou concevoir, détecter et/ou vérifier un nouveau peptide pénétrant dans les cellules (CPP) et un procédé permettant d'utiliser ce nouveau peptide CPP et/ou un nouvel usage d'un CPP connu pour une meilleure absorption cellulaire d'un effecteur cellulaire couplé à ce peptide CPP. La présente invention concerne également un procédé de prédiction ou de conception, détection et/ou vérification d'un nouveau peptide pénétrant dans les cellules (CPP) qui imitent l'activité de l'effecteur cellulaire et/ou inhibent l'activité de l'effecteur cellulaire. La présente invention concerne enfin l'utilisation de ce CPP pour traiter et/ou prévenir un état médical et l'utilisation de ce CPP pour la production d'une composition pharmaceutique en vue de traiter un état médical.
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Furthermore, the present invention also relates to a method for predicting or designing, detecting and/or verifying a novel cell-penetrating peptide (CPP) that mimics cellular effector activity and/or inhibits cellular effector activity. The present invention additionally relates to the use of said CPP for treating and/or preventing a medical condition and to the use of said CPP for the manufacture of a pharmaceutical composition for treating a medical condition. La présente invention concerne un procédé permettant de prédire ou concevoir, détecter et/ou vérifier un nouveau peptide pénétrant dans les cellules (CPP) et un procédé permettant d'utiliser ce nouveau peptide CPP et/ou un nouvel usage d'un CPP connu pour une meilleure absorption cellulaire d'un effecteur cellulaire couplé à ce peptide CPP. La présente invention concerne également un procédé de prédiction ou de conception, détection et/ou vérification d'un nouveau peptide pénétrant dans les cellules (CPP) qui imitent l'activité de l'effecteur cellulaire et/ou inhibent l'activité de l'effecteur cellulaire. La présente invention concerne enfin l'utilisation de ce CPP pour traiter et/ou prévenir un état médical et l'utilisation de ce CPP pour la production d'une composition pharmaceutique en vue de traiter un état médical.</description><edition>7</edition><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20031224&DB=EPODOC&CC=WO&NR=03106491A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20031224&DB=EPODOC&CC=WO&NR=03106491A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SOOMETS, URSEL</creatorcontrib><creatorcontrib>POOGA, MARGUS</creatorcontrib><creatorcontrib>MEIKAS, ANNE</creatorcontrib><creatorcontrib>EL-ANDALOUSSI, SAMIR</creatorcontrib><creatorcontrib>ELMQUIST, ANNA</creatorcontrib><creatorcontrib>METSIS, MADIS</creatorcontrib><creatorcontrib>LUNDBERG, PONTUS</creatorcontrib><creatorcontrib>ZORKO, MATJAZ</creatorcontrib><creatorcontrib>KILK, KALLE</creatorcontrib><creatorcontrib>LANGEL, UELO</creatorcontrib><creatorcontrib>HAELLBRINK, MATTIAS</creatorcontrib><creatorcontrib>LINDGREN, MARIA</creatorcontrib><creatorcontrib>OESTENSSON, CLAES, GOERAN</creatorcontrib><creatorcontrib>JAERVER, PETER</creatorcontrib><creatorcontrib>KOGERMAN, PRIIT</creatorcontrib><creatorcontrib>GRAESLUND, ASTRID</creatorcontrib><creatorcontrib>SAAR, KUELLIKI</creatorcontrib><creatorcontrib>BUDIHNA, METKA</creatorcontrib><creatorcontrib>VALKNA, ANDREAS</creatorcontrib><creatorcontrib>ERIKSSON, GOERAN</creatorcontrib><title>CELL PENETRATING PEPTIDES</title><description>The present invention relates to a method for predicting or designing, detecting, and/or verifying a novel cell-penetrating peptide (CPP) and to a method for using said new CPP and/or a novel usage of a known CPP for an improved cellular uptake of a cellular effector, coupled to said CPP. Furthermore, the present invention also relates to a method for predicting or designing, detecting and/or verifying a novel cell-penetrating peptide (CPP) that mimics cellular effector activity and/or inhibits cellular effector activity. The present invention additionally relates to the use of said CPP for treating and/or preventing a medical condition and to the use of said CPP for the manufacture of a pharmaceutical composition for treating a medical condition. La présente invention concerne un procédé permettant de prédire ou concevoir, détecter et/ou vérifier un nouveau peptide pénétrant dans les cellules (CPP) et un procédé permettant d'utiliser ce nouveau peptide CPP et/ou un nouvel usage d'un CPP connu pour une meilleure absorption cellulaire d'un effecteur cellulaire couplé à ce peptide CPP. La présente invention concerne également un procédé de prédiction ou de conception, détection et/ou vérification d'un nouveau peptide pénétrant dans les cellules (CPP) qui imitent l'activité de l'effecteur cellulaire et/ou inhibent l'activité de l'effecteur cellulaire. La présente invention concerne enfin l'utilisation de ce CPP pour traiter et/ou prévenir un état médical et l'utilisation de ce CPP pour la production d'une composition pharmaceutique en vue de traiter un état médical.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJB0dvXxUQhw9XMNCXIM8fRzB7IDQjxdXIN5GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakl8uL-BsaGBmYmloaORMTFqABg6IB0</recordid><startdate>20031224</startdate><enddate>20031224</enddate><creator>SOOMETS, URSEL</creator><creator>POOGA, MARGUS</creator><creator>MEIKAS, ANNE</creator><creator>EL-ANDALOUSSI, SAMIR</creator><creator>ELMQUIST, ANNA</creator><creator>METSIS, MADIS</creator><creator>LUNDBERG, PONTUS</creator><creator>ZORKO, MATJAZ</creator><creator>KILK, KALLE</creator><creator>LANGEL, UELO</creator><creator>HAELLBRINK, MATTIAS</creator><creator>LINDGREN, MARIA</creator><creator>OESTENSSON, CLAES, GOERAN</creator><creator>JAERVER, PETER</creator><creator>KOGERMAN, PRIIT</creator><creator>GRAESLUND, ASTRID</creator><creator>SAAR, KUELLIKI</creator><creator>BUDIHNA, METKA</creator><creator>VALKNA, ANDREAS</creator><creator>ERIKSSON, GOERAN</creator><scope>EVB</scope></search><sort><creationdate>20031224</creationdate><title>CELL PENETRATING PEPTIDES</title><author>SOOMETS, URSEL ; 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Furthermore, the present invention also relates to a method for predicting or designing, detecting and/or verifying a novel cell-penetrating peptide (CPP) that mimics cellular effector activity and/or inhibits cellular effector activity. The present invention additionally relates to the use of said CPP for treating and/or preventing a medical condition and to the use of said CPP for the manufacture of a pharmaceutical composition for treating a medical condition. La présente invention concerne un procédé permettant de prédire ou concevoir, détecter et/ou vérifier un nouveau peptide pénétrant dans les cellules (CPP) et un procédé permettant d'utiliser ce nouveau peptide CPP et/ou un nouvel usage d'un CPP connu pour une meilleure absorption cellulaire d'un effecteur cellulaire couplé à ce peptide CPP. La présente invention concerne également un procédé de prédiction ou de conception, détection et/ou vérification d'un nouveau peptide pénétrant dans les cellules (CPP) qui imitent l'activité de l'effecteur cellulaire et/ou inhibent l'activité de l'effecteur cellulaire. La présente invention concerne enfin l'utilisation de ce CPP pour traiter et/ou prévenir un état médical et l'utilisation de ce CPP pour la production d'une composition pharmaceutique en vue de traiter un état médical.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
title	CELL PENETRATING PEPTIDES
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