TOLL-LIKE RECEPTOR 11

The invention describes isolated Toll-like receptor 11 ("TLR11 ") and Toll­like receptor 12 ("TLR12") polypeptides as well as isolated variants and fragments thereof and the isolated nucleic acids encoding them. The invention also describes vectors and host cells containing nucle...

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1. Verfasser: MEDZHITOV, RUSLAN, M
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description The invention describes isolated Toll-like receptor 11 ("TLR11 ") and Toll­like receptor 12 ("TLR12") polypeptides as well as isolated variants and fragments thereof and the isolated nucleic acids encoding them. The invention also describes vectors and host cells containing nucleic acid encoding a TLR11 or a TLR12 polypeptide and methods for producing a TLR11 or a TLR12 polypeptide. Also described are methods for screening for compounds which modulate TLR11 or TLR12 activity. L'invention concerne des polypeptides isolés, à savoir récepteur de type Toll 11 ("TLR11") et récepteur de type Toll 12 ("TLR12"), ainsi que des variants et fragments isolés correspondants, et des acides nucléiques isolés codant ces polypeptides. L'invention concerne également des vecteurs et des cellules hôtes renfermant un acide nucléique qui code ce type de polypeptide, et des procédés relatifs à l'élaboration des polypetides en question. L'invention concerne en outre des procédés relatifs au criblage de composés qui modulent l'activité desdits polypeptides.
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The invention also describes vectors and host cells containing nucleic acid encoding a TLR11 or a TLR12 polypeptide and methods for producing a TLR11 or a TLR12 polypeptide. Also described are methods for screening for compounds which modulate TLR11 or TLR12 activity. L'invention concerne des polypeptides isolés, à savoir récepteur de type Toll 11 ("TLR11") et récepteur de type Toll 12 ("TLR12"), ainsi que des variants et fragments isolés correspondants, et des acides nucléiques isolés codant ces polypeptides. L'invention concerne également des vecteurs et des cellules hôtes renfermant un acide nucléique qui code ce type de polypeptide, et des procédés relatifs à l'élaboration des polypetides en question. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
title TOLL-LIKE RECEPTOR 11
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