N-(3-RIFAMYCINYL)-CARBAMATES, METHOD OF PREPARING THEM AND THEIR USE FOR TREATING AND PREVENTING TUBERCULOSIS

The present invention relates to novel N-(3-rifamycinyl)-derivatives, namely N-(3-rifamycinyl)-carbamates, methods of their preparation and their use for the production of pharmaceutical preparations. The invention also concerns a composition and a method for treating or preventing mycobacterial inf...

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Hauptverfasser:	NEDEYALKOVA, ZOYA, ANDONOVA, DEKIN, SASHKO, IVANOV, SHAFI, JAMILA, HALADGOVA, SVETLANA, TZVETKOVA, KUEHNE, RALPH, MEKENYAN, OVANES, ANDREW, PETER, WILLIAM, GROZDANOV, ASENOV, SHARPE, JASON, ANTHONY, DIMOV, DIMCHO, IVANOV, PENEV, PAVEL, NENOV, ATANASOVA, ISKRA, TODOROVA, PARASKEVOVA, STEVKA, TZVETKOVA, SCHUEUERMANN, GERRIT, MINCHEVA, DESISLAVA, TODOROVA, ANGELOVA, NELY, TZONEVA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel N-(3-rifamycinyl)-derivatives, namely N-(3-rifamycinyl)-carbamates, methods of their preparation and their use for the production of pharmaceutical preparations. The invention also concerns a composition and a method for treating or preventing mycobacterial infections, especially tuberculosis. La présente invention concerne de nouveaux dérivés de N-(3-rifamycinyl), à savoir des carbamates N-(3-rifamycinyl), des procédés pour leur préparation et leur utilisation pour la production de préparations pharmaceutiques. L'invention traite également d'une composition et d'un procédé de traitement ou de prévention d'inventions mycobactériennes, en particulier de la tuberculose.