DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH NEUROPEPTIDE FF RECEPTOR 2 (NPFF2)

The invention provides a human NPFF2 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD and asthma, and genito-urological disorders. The invention also provides assays for the identifica...

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Hauptverfasser: GOLZ, STEFAN, BRUEGGEMEIER, ULF, WEINGAERTNER, BERNHARD
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creator GOLZ, STEFAN
BRUEGGEMEIER, ULF
WEINGAERTNER, BERNHARD
description The invention provides a human NPFF2 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD and asthma, and genito-urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD and asthma, and genito-urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of NPFF2 as well as pharmaceutical compositions comprising such compounds. L'invention concerne un NPFF2 humain associé aux maladies hématologiques, aux maladies cardio-vasculaires, aux troubles du système nerveux central et du système nerveux périphérique, aux maladies respiratoires comme la broncho-pneumopathie chronique obstructive et l'asthme et les troubles génito-urologiques. L'invention concerne également des dosages permettant d'identifier des composés présentant une grande utilité pour le traitement ou la prévention de maladies hématologiques, cardio-vasculaires, de troubles du système nerveux périphérique et du système nerveux central, de maladies respiratoires comme la broncho-pneumopathie chronique obstructive et l'asthme et les troubles génito-urologiques. L'invention concerne également des composés qui se lient et/ou activent ou inhibent l'activité de NPFF2 ainsi que des compositions pharmaceutiques comprenant ces composés.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH NEUROPEPTIDE FF RECEPTOR 2 (NPFF2)
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