GAS-PLASMA TREATMENT OF IMPLANTS

An implant for use in biological/biomedical applications may be prepared by subjecting a substrate to a gas-plasma treatment. The substrate may be a biocompatible material, including metals, ceramics, and polymers. More specifically, the substrate may be a bioresorbable polymer. The gas-plasma treat...

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Hauptverfasser: BAILEY, STEVEN, R, AGRAWAL, C., MAULI, POLAN, JODIE, L
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AGRAWAL, C., MAULI
POLAN, JODIE, L
description An implant for use in biological/biomedical applications may be prepared by subjecting a substrate to a gas-plasma treatment. The substrate may be a biocompatible material, including metals, ceramics, and polymers. More specifically, the substrate may be a bioresorbable polymer. The gas-plasma treatment may include subjecting the substrate to a plasma formed by a reactive gas. The gas-plasma treatment may be performed for a chosen duration at a radio frequency within a temperature range, a pressure range, and a supplied energy range. The substrate may be exposed to living cells, such that some of the living cells become coupled to the substrate. Gas-plasma treatment parameters may be chosen such that the living cells coupled to the treated substrate produce more of a cellular product than living cells coupled to an untreated substrate. L'invention concerne un implant utilisable dans des applications biologiques/biomédicales lequel peut être préparé selon un procédé consistant à soumettre un substrat à un traitement par plasma. Le substrat peut être un matériau biocompatible, y compris les métaux, la céramique et les polymères. Plus particulièrement, le substrat peut être un polymère biorésorbable. Le traitement par plasma peut consister à soumettre le substrat à un plasma formé par un gaz réactif. Ce traitement peut être réalisé pendant un laps de temps choisi à une radiofréquence dans une gamme de températures, une gamme de pressions et une gamme d'énergies fournies. Le substrat peut être exposé à des cellules vivantes de telle sorte que certaines de ces cellules vivantes fusionnent avec le substrat. Les paramètres du traitement par plasma peuvent être choisis de telle sorte que les cellules vivantes incorporées dans le substrat traité produisent plus d'un produit cellulaire que les cellules vivantes incorporées dans un substrat non traité.
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The substrate may be a biocompatible material, including metals, ceramics, and polymers. More specifically, the substrate may be a bioresorbable polymer. The gas-plasma treatment may include subjecting the substrate to a plasma formed by a reactive gas. The gas-plasma treatment may be performed for a chosen duration at a radio frequency within a temperature range, a pressure range, and a supplied energy range. The substrate may be exposed to living cells, such that some of the living cells become coupled to the substrate. Gas-plasma treatment parameters may be chosen such that the living cells coupled to the treated substrate produce more of a cellular product than living cells coupled to an untreated substrate. L'invention concerne un implant utilisable dans des applications biologiques/biomédicales lequel peut être préparé selon un procédé consistant à soumettre un substrat à un traitement par plasma. 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Le substrat peut être un matériau biocompatible, y compris les métaux, la céramique et les polymères. Plus particulièrement, le substrat peut être un polymère biorésorbable. Le traitement par plasma peut consister à soumettre le substrat à un plasma formé par un gaz réactif. Ce traitement peut être réalisé pendant un laps de temps choisi à une radiofréquence dans une gamme de températures, une gamme de pressions et une gamme d'énergies fournies. Le substrat peut être exposé à des cellules vivantes de telle sorte que certaines de ces cellules vivantes fusionnent avec le substrat. 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STENTS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>ENZYMOLOGY</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PEPTIDES</topic><topic>PERFORMING OPERATIONS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>PROSTHESES</topic><topic>SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDEDFOR</topic><topic>SHAPING OR JOINING OF PLASTICS</topic><topic>SPIRITS</topic><topic>TRANSPORTING</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><topic>VINEGAR</topic><topic>WINE</topic><topic>WORKING OF PLASTICS</topic><topic>WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL</topic><toplevel>online_resources</toplevel><creatorcontrib>BAILEY, STEVEN, R</creatorcontrib><creatorcontrib>AGRAWAL, C., MAULI</creatorcontrib><creatorcontrib>POLAN, JODIE, L</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BAILEY, STEVEN, R</au><au>AGRAWAL, C., MAULI</au><au>POLAN, JODIE, L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>GAS-PLASMA TREATMENT OF IMPLANTS</title><date>2004-02-19</date><risdate>2004</risdate><abstract>An implant for use in biological/biomedical applications may be prepared by subjecting a substrate to a gas-plasma treatment. The substrate may be a biocompatible material, including metals, ceramics, and polymers. More specifically, the substrate may be a bioresorbable polymer. The gas-plasma treatment may include subjecting the substrate to a plasma formed by a reactive gas. The gas-plasma treatment may be performed for a chosen duration at a radio frequency within a temperature range, a pressure range, and a supplied energy range. The substrate may be exposed to living cells, such that some of the living cells become coupled to the substrate. Gas-plasma treatment parameters may be chosen such that the living cells coupled to the treated substrate produce more of a cellular product than living cells coupled to an untreated substrate. L'invention concerne un implant utilisable dans des applications biologiques/biomédicales lequel peut être préparé selon un procédé consistant à soumettre un substrat à un traitement par plasma. Le substrat peut être un matériau biocompatible, y compris les métaux, la céramique et les polymères. Plus particulièrement, le substrat peut être un polymère biorésorbable. Le traitement par plasma peut consister à soumettre le substrat à un plasma formé par un gaz réactif. Ce traitement peut être réalisé pendant un laps de temps choisi à une radiofréquence dans une gamme de températures, une gamme de pressions et une gamme d'énergies fournies. Le substrat peut être exposé à des cellules vivantes de telle sorte que certaines de ces cellules vivantes fusionnent avec le substrat. Les paramètres du traitement par plasma peuvent être choisis de telle sorte que les cellules vivantes incorporées dans le substrat traité produisent plus d'un produit cellulaire que les cellules vivantes incorporées dans un substrat non traité.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
BANDAGES, DRESSINGS OR ABSORBENT PADS
BEER
BIOCHEMISTRY
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
ENZYMOLOGY
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PEPTIDES
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
PROSTHESES
SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDEDFOR
SHAPING OR JOINING OF PLASTICS
SPIRITS
TRANSPORTING
TREATMENT OR PROTECTION OF EYES OR EARS
VINEGAR
WINE
WORKING OF PLASTICS
WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
title GAS-PLASMA TREATMENT OF IMPLANTS
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