IMPROVED SYNTHESIS OF POLYANHYRIDES
The present invention provides a method for forming compounds of Formula HO-C(=O)R -X-R -X-R -C(=O)-O-H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R is group that will provide the therapeuticall...
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creator | PUDIL, BRYANT, J WOOD, RICHARD, D UHRICH, KATHRYN, E SCHMELTZER, ROBERT, C ANASTASION, THEODORE, JAMES |
description | The present invention provides a method for forming compounds of Formula HO-C(=O)R -X-R -X-R -C(=O)-O-H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R is group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and R is a linking group.
la présente invention concerne une méthode de fabrication de composés représentés par la formule HO-C(=O)R -X-R -X-R -C(=O)-O-H. Selon cette formule, le composé (I) peut être polymérisé et produire un polymère renfermant des composés actifs au plan thérapeutique. Dans les composés de l'invention, chaque R représente un groupe fournissant le composé thérapeutiquement actif par hydrolyse du polymère; chaque X est indépendamment une liaison ester ou une liaison amide ; et R est un groupe de liaison. |
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la présente invention concerne une méthode de fabrication de composés représentés par la formule HO-C(=O)R -X-R -X-R -C(=O)-O-H. Selon cette formule, le composé (I) peut être polymérisé et produire un polymère renfermant des composés actifs au plan thérapeutique. Dans les composés de l'invention, chaque R représente un groupe fournissant le composé thérapeutiquement actif par hydrolyse du polymère; chaque X est indépendamment une liaison ester ou une liaison amide ; et R est un groupe de liaison.</description><edition>7</edition><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; HUMAN NECESSITIES ; HYGIENE ; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; ORGANIC MACROMOLECULAR COMPOUNDS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030605&DB=EPODOC&CC=WO&NR=03046034A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25555,76308</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030605&DB=EPODOC&CC=WO&NR=03046034A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PUDIL, BRYANT, J</creatorcontrib><creatorcontrib>WOOD, RICHARD, D</creatorcontrib><creatorcontrib>UHRICH, KATHRYN, E</creatorcontrib><creatorcontrib>SCHMELTZER, ROBERT, C</creatorcontrib><creatorcontrib>ANASTASION, THEODORE, JAMES</creatorcontrib><title>IMPROVED SYNTHESIS OF POLYANHYRIDES</title><description>The present invention provides a method for forming compounds of Formula HO-C(=O)R -X-R -X-R -C(=O)-O-H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R is group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and R is a linking group.
la présente invention concerne une méthode de fabrication de composés représentés par la formule HO-C(=O)R -X-R -X-R -C(=O)-O-H. Selon cette formule, le composé (I) peut être polymérisé et produire un polymère renfermant des composés actifs au plan thérapeutique. Dans les composés de l'invention, chaque R représente un groupe fournissant le composé thérapeutiquement actif par hydrolyse du polymère; chaque X est indépendamment une liaison ester ou une liaison amide ; et R est un groupe de liaison.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD29A0I8g9zdVEIjvQL8XAN9gxW8HdTCPD3iXT084gM8nRxDeZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHh_gbGBiZmBsYmjkbGxKgBAIcoIzA</recordid><startdate>20030605</startdate><enddate>20030605</enddate><creator>PUDIL, BRYANT, J</creator><creator>WOOD, RICHARD, D</creator><creator>UHRICH, KATHRYN, E</creator><creator>SCHMELTZER, ROBERT, C</creator><creator>ANASTASION, THEODORE, JAMES</creator><scope>EVB</scope></search><sort><creationdate>20030605</creationdate><title>IMPROVED SYNTHESIS OF POLYANHYRIDES</title><author>PUDIL, BRYANT, J ; WOOD, RICHARD, D ; UHRICH, KATHRYN, E ; SCHMELTZER, ROBERT, C ; ANASTASION, THEODORE, JAMES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO03046034A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2003</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><toplevel>online_resources</toplevel><creatorcontrib>PUDIL, BRYANT, J</creatorcontrib><creatorcontrib>WOOD, RICHARD, D</creatorcontrib><creatorcontrib>UHRICH, KATHRYN, E</creatorcontrib><creatorcontrib>SCHMELTZER, ROBERT, C</creatorcontrib><creatorcontrib>ANASTASION, THEODORE, JAMES</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PUDIL, BRYANT, J</au><au>WOOD, RICHARD, D</au><au>UHRICH, KATHRYN, E</au><au>SCHMELTZER, ROBERT, C</au><au>ANASTASION, THEODORE, JAMES</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IMPROVED SYNTHESIS OF POLYANHYRIDES</title><date>2003-06-05</date><risdate>2003</risdate><abstract>The present invention provides a method for forming compounds of Formula HO-C(=O)R -X-R -X-R -C(=O)-O-H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R is group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and R is a linking group.
la présente invention concerne une méthode de fabrication de composés représentés par la formule HO-C(=O)R -X-R -X-R -C(=O)-O-H. Selon cette formule, le composé (I) peut être polymérisé et produire un polymère renfermant des composés actifs au plan thérapeutique. Dans les composés de l'invention, chaque R représente un groupe fournissant le composé thérapeutiquement actif par hydrolyse du polymère; chaque X est indépendamment une liaison ester ou une liaison amide ; et R est un groupe de liaison.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP |
title | IMPROVED SYNTHESIS OF POLYANHYRIDES |
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