CONTROLLED RELEASE COMPOSITIONS FOR MACROLIDE ANTIMICROBIAL AGENTS
The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred embodiment the drug is combined with a practically water insoluble polymer an optimizing agent and optio...
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| creator | KHAPRA, PANKAJ GOSAVI, ARUN, S HUSSAIN, JAVED |
| description | The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred embodiment the drug is combined with a practically water insoluble polymer an optimizing agent and optional additives to produce a controlled release of therapeutic agent when compositions is exposed to aqueous environment.
L'invention concerne une composition pharmaceutique à libération contrôlée d'un médicament labile en milieu acide, peu soluble, possédant un profil de solubilité dépendant du pH dans un environnement aqueux. Dans un mode de réalisation préféré, ce médicament est combiné à un agent d'optimisation pratiquement insoluble dans l'eau et à des additifs facultatifs pour obtenir la libération contrôlée d'un agent thérapeutique lorsque ces compositions sont exposées à un environnement aqueux. |
| format | Patent |
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L'invention concerne une composition pharmaceutique à libération contrôlée d'un médicament labile en milieu acide, peu soluble, possédant un profil de solubilité dépendant du pH dans un environnement aqueux. Dans un mode de réalisation préféré, ce médicament est combiné à un agent d'optimisation pratiquement insoluble dans l'eau et à des additifs facultatifs pour obtenir la libération contrôlée d'un agent thérapeutique lorsque ces compositions sont exposées à un environnement aqueux.</description><edition>7</edition><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030508&DB=EPODOC&CC=WO&NR=03037304A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030508&DB=EPODOC&CC=WO&NR=03037304A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KHAPRA, PANKAJ</creatorcontrib><creatorcontrib>GOSAVI, ARUN, S</creatorcontrib><creatorcontrib>HUSSAIN, JAVED</creatorcontrib><title>CONTROLLED RELEASE COMPOSITIONS FOR MACROLIDE ANTIMICROBIAL AGENTS</title><description>The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred embodiment the drug is combined with a practically water insoluble polymer an optimizing agent and optional additives to produce a controlled release of therapeutic agent when compositions is exposed to aqueous environment.
L'invention concerne une composition pharmaceutique à libération contrôlée d'un médicament labile en milieu acide, peu soluble, possédant un profil de solubilité dépendant du pH dans un environnement aqueux. Dans un mode de réalisation préféré, ce médicament est combiné à un agent d'optimisation pratiquement insoluble dans l'eau et à des additifs facultatifs pour obtenir la libération contrôlée d'un agent thérapeutique lorsque ces compositions sont exposées à un environnement aqueux.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBy9vcLCfL38XF1UQhy9XF1DHZVcPb3DfAP9gzx9PcLVnDzD1LwdXQGKvF0cVVw9Avx9PUE8pw8HX0UHN1d_UKCeRhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYnJqXmpJfLi_gbGBsbmxgYmjoTExagAriSuS</recordid><startdate>20030508</startdate><enddate>20030508</enddate><creator>KHAPRA, PANKAJ</creator><creator>GOSAVI, ARUN, S</creator><creator>HUSSAIN, JAVED</creator><scope>EVB</scope></search><sort><creationdate>20030508</creationdate><title>CONTROLLED RELEASE COMPOSITIONS FOR MACROLIDE ANTIMICROBIAL AGENTS</title><author>KHAPRA, PANKAJ ; GOSAVI, ARUN, S ; HUSSAIN, JAVED</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO03037304A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2003</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KHAPRA, PANKAJ</creatorcontrib><creatorcontrib>GOSAVI, ARUN, S</creatorcontrib><creatorcontrib>HUSSAIN, JAVED</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KHAPRA, PANKAJ</au><au>GOSAVI, ARUN, S</au><au>HUSSAIN, JAVED</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CONTROLLED RELEASE COMPOSITIONS FOR MACROLIDE ANTIMICROBIAL AGENTS</title><date>2003-05-08</date><risdate>2003</risdate><abstract>The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred embodiment the drug is combined with a practically water insoluble polymer an optimizing agent and optional additives to produce a controlled release of therapeutic agent when compositions is exposed to aqueous environment.
L'invention concerne une composition pharmaceutique à libération contrôlée d'un médicament labile en milieu acide, peu soluble, possédant un profil de solubilité dépendant du pH dans un environnement aqueux. Dans un mode de réalisation préféré, ce médicament est combiné à un agent d'optimisation pratiquement insoluble dans l'eau et à des additifs facultatifs pour obtenir la libération contrôlée d'un agent thérapeutique lorsque ces compositions sont exposées à un environnement aqueux.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CONTROLLED RELEASE COMPOSITIONS FOR MACROLIDE ANTIMICROBIAL AGENTS |
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