GALECTIN-14 THERAPEUTIC MOLECULE AND USES THEREOF

The present invention relates generally to a novel galectin and to derivatives, homologues, analogues, chemical equivalents and mimetics thereof capable of modulating an immune response and, in particularly, an inflammatory response. More particularly, the present invention relates to ecalectin-like...

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Hauptverfasser: DUNPHY, JILLIAN, LEE, NASH, ANDREW, YOUNG, ANNA, RACHEL, MEEUSEN, ELZA, NICOLE, THERESIA, BARCHAM, GARRY
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creator DUNPHY, JILLIAN, LEE
NASH, ANDREW
YOUNG, ANNA, RACHEL
MEEUSEN, ELZA, NICOLE, THERESIA
BARCHAM, GARRY
description The present invention relates generally to a novel galectin and to derivatives, homologues, analogues, chemical equivalents and mimetics thereof capable of modulating an immune response and, in particularly, an inflammatory response. More particularly, the present invention relates to ecalectin-like galectin (herein referred to as "galectin-14") and to derivatives, homologues, analogues, chemical equivalents and mimetics of said protein sequence. The present invention also contemplates genetic sequences encoding said galectin and derivatives, homologues, analogues, chemical equivalents and mimetics thereof. The molecules of the present invention are useful in a range of therapeutic, prophylactic and diagnostic applications. L'invention concerne, de façon générale, une galectine et des dérivés, homologues, analogues, équivalents chimiques et substances mimétiques de cette galectine pouvant moduler une réponse immune et, en particulier, une réponse inflammatoire. Elle concerne, plus particulièrement, une galectine de type écalectine (dénommée ici "galectine-14") et des dérivés, homologues, analogues, équivalents chimiques et substances mimétiques de cette séquence de protéine. Elle concerne enfin des séquences génétiques codant pour cette galectine et ses dérivés, homologues, analogues, équivalents et substances mimétiques. Les molécules de cette invention sont utiles dans le domaine des applications thérapeutiques, prophylactiques et de diagnostic.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title GALECTIN-14 THERAPEUTIC MOLECULE AND USES THEREOF
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