NOVEL PDEs AND USES THEREOF

The present invention provides isolated full-length nucleic acid molecules encoding the PDE proteins invention and uses thereof. The nucleic acid molecule of the invention also include peptide nucleic acids (PNA) and antisense molecules that react with the above-mentioned nucleic acids. The inventio...

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Hauptverfasser: RASCON, ANA, ZORAGHI, ROYA, GONG, KEWEI, SEEBECK, THOMAS, GLAVAS, NATALIE, KUNZ, STEFAN, BEAVO, JOSEPH, A, SODERLING, SCOTT, HAYDN
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creator RASCON, ANA
ZORAGHI, ROYA
GONG, KEWEI
SEEBECK, THOMAS
GLAVAS, NATALIE
KUNZ, STEFAN
BEAVO, JOSEPH, A
SODERLING, SCOTT, HAYDN
description The present invention provides isolated full-length nucleic acid molecules encoding the PDE proteins invention and uses thereof. The nucleic acid molecule of the invention also include peptide nucleic acids (PNA) and antisense molecules that react with the above-mentioned nucleic acids. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of PDE proteins. The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins. L'invention concerne des molécules d'acides nucléiques isolées pleine longueur codant la phosphodiestérase décrite dans l'invention, et des procédés d'utilisation correspondants. Les molécules considérées englobent des acides nucléiques peptidiques, et des molécules antisens qui réagissent avec elles. L'invention concerne également des agonistes, des anticorps, des antagonistes ou des inhibiteurs vis-à-vis de l'activité de la phosphodiestérase. Les compositions considérées sont utiles pour le diagnostic, la prévention ou le traitement des troubles associés à la présence ou à l'absence de ce type de protéine.
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The nucleic acid molecule of the invention also include peptide nucleic acids (PNA) and antisense molecules that react with the above-mentioned nucleic acids. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of PDE proteins. The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins. L'invention concerne des molécules d'acides nucléiques isolées pleine longueur codant la phosphodiestérase décrite dans l'invention, et des procédés d'utilisation correspondants. Les molécules considérées englobent des acides nucléiques peptidiques, et des molécules antisens qui réagissent avec elles. L'invention concerne également des agonistes, des anticorps, des antagonistes ou des inhibiteurs vis-à-vis de l'activité de la phosphodiestérase. Les compositions considérées sont utiles pour le diagnostic, la prévention ou le traitement des troubles associés à la présence ou à l'absence de ce type de protéine.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
VINEGAR
WINE
title NOVEL PDEs AND USES THEREOF
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