NOVEL PDEs AND USES THEREOF
The present invention provides isolated full-length nucleic acid molecules encoding the PDE proteins invention and uses thereof. The nucleic acid molecule of the invention also include peptide nucleic acids (PNA) and antisense molecules that react with the above-mentioned nucleic acids. The inventio...
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creator | RASCON, ANA ZORAGHI, ROYA GONG, KEWEI SEEBECK, THOMAS GLAVAS, NATALIE KUNZ, STEFAN BEAVO, JOSEPH, A SODERLING, SCOTT, HAYDN |
description | The present invention provides isolated full-length nucleic acid molecules encoding the PDE proteins invention and uses thereof. The nucleic acid molecule of the invention also include peptide nucleic acids (PNA) and antisense molecules that react with the above-mentioned nucleic acids. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of PDE proteins.
The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins.
L'invention concerne des molécules d'acides nucléiques isolées pleine longueur codant la phosphodiestérase décrite dans l'invention, et des procédés d'utilisation correspondants. Les molécules considérées englobent des acides nucléiques peptidiques, et des molécules antisens qui réagissent avec elles. L'invention concerne également des agonistes, des anticorps, des antagonistes ou des inhibiteurs vis-à-vis de l'activité de la phosphodiestérase. Les compositions considérées sont utiles pour le diagnostic, la prévention ou le traitement des troubles associés à la présence ou à l'absence de ce type de protéine. |
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The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins.
L'invention concerne des molécules d'acides nucléiques isolées pleine longueur codant la phosphodiestérase décrite dans l'invention, et des procédés d'utilisation correspondants. Les molécules considérées englobent des acides nucléiques peptidiques, et des molécules antisens qui réagissent avec elles. L'invention concerne également des agonistes, des anticorps, des antagonistes ou des inhibiteurs vis-à-vis de l'activité de la phosphodiestérase. Les compositions considérées sont utiles pour le diagnostic, la prévention ou le traitement des troubles associés à la présence ou à l'absence de ce type de protéine.</description><edition>7</edition><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; DERIVATIVES THEREOF ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; SUGARS ; VINEGAR ; WINE</subject><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20020321&DB=EPODOC&CC=WO&NR=0222661A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25573,76557</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20020321&DB=EPODOC&CC=WO&NR=0222661A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RASCON, ANA</creatorcontrib><creatorcontrib>ZORAGHI, ROYA</creatorcontrib><creatorcontrib>GONG, KEWEI</creatorcontrib><creatorcontrib>SEEBECK, THOMAS</creatorcontrib><creatorcontrib>GLAVAS, NATALIE</creatorcontrib><creatorcontrib>KUNZ, STEFAN</creatorcontrib><creatorcontrib>BEAVO, JOSEPH, A</creatorcontrib><creatorcontrib>SODERLING, SCOTT, HAYDN</creatorcontrib><title>NOVEL PDEs AND USES THEREOF</title><description>The present invention provides isolated full-length nucleic acid molecules encoding the PDE proteins invention and uses thereof. The nucleic acid molecule of the invention also include peptide nucleic acids (PNA) and antisense molecules that react with the above-mentioned nucleic acids. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of PDE proteins.
The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins.
L'invention concerne des molécules d'acides nucléiques isolées pleine longueur codant la phosphodiestérase décrite dans l'invention, et des procédés d'utilisation correspondants. Les molécules considérées englobent des acides nucléiques peptidiques, et des molécules antisens qui réagissent avec elles. L'invention concerne également des agonistes, des anticorps, des antagonistes ou des inhibiteurs vis-à-vis de l'activité de la phosphodiestérase. Les compositions considérées sont utiles pour le diagnostic, la prévention ou le traitement des troubles associés à la présence ou à l'absence de ce type de protéine.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJD28w9z9VEIcHEtVnD0c1EIDXYNVgjxcA1y9XfjYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXx4f4GRkZGZmaGjkbGRCgBABCdICQ</recordid><startdate>20020321</startdate><enddate>20020321</enddate><creator>RASCON, ANA</creator><creator>ZORAGHI, ROYA</creator><creator>GONG, KEWEI</creator><creator>SEEBECK, THOMAS</creator><creator>GLAVAS, NATALIE</creator><creator>KUNZ, STEFAN</creator><creator>BEAVO, JOSEPH, A</creator><creator>SODERLING, SCOTT, HAYDN</creator><scope>EVB</scope></search><sort><creationdate>20020321</creationdate><title>NOVEL PDEs AND USES THEREOF</title><author>RASCON, ANA ; ZORAGHI, ROYA ; GONG, KEWEI ; SEEBECK, THOMAS ; GLAVAS, NATALIE ; KUNZ, STEFAN ; BEAVO, JOSEPH, A ; SODERLING, SCOTT, HAYDN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO0222661A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2002</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>RASCON, ANA</creatorcontrib><creatorcontrib>ZORAGHI, ROYA</creatorcontrib><creatorcontrib>GONG, KEWEI</creatorcontrib><creatorcontrib>SEEBECK, THOMAS</creatorcontrib><creatorcontrib>GLAVAS, NATALIE</creatorcontrib><creatorcontrib>KUNZ, STEFAN</creatorcontrib><creatorcontrib>BEAVO, JOSEPH, A</creatorcontrib><creatorcontrib>SODERLING, SCOTT, HAYDN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RASCON, ANA</au><au>ZORAGHI, ROYA</au><au>GONG, KEWEI</au><au>SEEBECK, THOMAS</au><au>GLAVAS, NATALIE</au><au>KUNZ, STEFAN</au><au>BEAVO, JOSEPH, A</au><au>SODERLING, SCOTT, HAYDN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL PDEs AND USES THEREOF</title><date>2002-03-21</date><risdate>2002</risdate><abstract>The present invention provides isolated full-length nucleic acid molecules encoding the PDE proteins invention and uses thereof. The nucleic acid molecule of the invention also include peptide nucleic acids (PNA) and antisense molecules that react with the above-mentioned nucleic acids. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of PDE proteins.
The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins.
L'invention concerne des molécules d'acides nucléiques isolées pleine longueur codant la phosphodiestérase décrite dans l'invention, et des procédés d'utilisation correspondants. Les molécules considérées englobent des acides nucléiques peptidiques, et des molécules antisens qui réagissent avec elles. L'invention concerne également des agonistes, des anticorps, des antagonistes ou des inhibiteurs vis-à-vis de l'activité de la phosphodiestérase. Les compositions considérées sont utiles pour le diagnostic, la prévention ou le traitement des troubles associés à la présence ou à l'absence de ce type de protéine.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE |
title | NOVEL PDEs AND USES THEREOF |
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