TISSUE-ASSOCIATED PROTEINS AND THEIR USES

The present invention relates to the discovery of nucleic acids and proteins that are markers for specific normal or cancerous tissues. The identification of these markers has diagnostic uses in detecting cancer in a subject, as well as in determining the tissue of origin for a cancerous cell. These...

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Hauptverfasser: PRITCHARD, DAVID, DEMAS, VASILIKI, BROWN, JOSEPH, P, BURMER, GLENNA, C
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creator PRITCHARD, DAVID
DEMAS, VASILIKI
BROWN, JOSEPH, P
BURMER, GLENNA, C
description The present invention relates to the discovery of nucleic acids and proteins that are markers for specific normal or cancerous tissues. The identification of these markers has diagnostic uses in detecting cancer in a subject, as well as in determining the tissue of origin for a cancerous cell. These tissue-specific molecules further allow the tissue specific expression of a polynucleotide or protein of interest. In addition, the tissue-specific molecules of the invention have therapeutic applications for targeting compounds to a tissue of interest.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
title TISSUE-ASSOCIATED PROTEINS AND THEIR USES
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