ANTHOZOA DERIVED CHROMOPROTEINS, FLUORESCENT MUTANTS THEREOF AND METHODS FOR USING THE SAME

Nucleic acid compositions encoding Actiniidaen, e.g., Condylactin, chromoproteins and fluorescent mutants thereof, as well as the polypeptide compositions encoded by the same, are provided. The proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the...

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Hauptverfasser: FRADKOV, ARCADY, FEDOROVICH, LUKYANOV, SERGEY, ANATOLIEVICH, LUKYANOV, KONSTANTIN, ANATOLIEVICH
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LUKYANOV, SERGEY, ANATOLIEVICH
LUKYANOV, KONSTANTIN, ANATOLIEVICH
description Nucleic acid compositions encoding Actiniidaen, e.g., Condylactin, chromoproteins and fluorescent mutants thereof, as well as the polypeptide compositions encoded by the same, are provided. The proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein. Also of interest are proteins that are substantially similar to, or mutants of, the above specific proteins, including non-aggregating mutants and mutants with modulated oligomerization characteristics as compared to wild type. Also provided are fragments of the nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications, e.g., that include the subject nucleic acid compositions, are provided. L'invention concerne des compositions d'acide nucléique codant pour des chromoprotéines d'actinies, p. ex. condylactine, et des mutants fluorescents de celles-ci ; ainsi que les compositions polypeptidiques codées par ceux-ci. Les protéines intéressantes sont des protéines colorées et/ou fluorescentes, cette caractéristique étant obtenue par l'interaction entre deux ou davantage de résidus de la protéine ; d'autres protéines intéressantes sont sensiblement similaires à ces protéines spécifiques, ou constituent des mutants de celles-ci, y compris des mutants non agrégants et des mutants possédant des caractéristiques d'oligomérisation modulées par comparaison avec le type sauvage. L'invention concerne aussi des fragments des acides nucléiques et les peptides codés par ceux-ci, ainsi que des anticorps dirigés contre les protéines en question et des cellules et organismes transgéniques. Cette protéine et ces compositions d'acide nucléique sont utiles dans diverses applications différentes. L'invention concerne également des trousses s'utilisant dans ces applications, p. ex. incluant lesdites compositions d'acide nucléique.
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The proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein. Also of interest are proteins that are substantially similar to, or mutants of, the above specific proteins, including non-aggregating mutants and mutants with modulated oligomerization characteristics as compared to wild type. Also provided are fragments of the nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications, e.g., that include the subject nucleic acid compositions, are provided. L'invention concerne des compositions d'acide nucléique codant pour des chromoprotéines d'actinies, p. ex. condylactine, et des mutants fluorescents de celles-ci ; ainsi que les compositions polypeptidiques codées par ceux-ci. Les protéines intéressantes sont des protéines colorées et/ou fluorescentes, cette caractéristique étant obtenue par l'interaction entre deux ou davantage de résidus de la protéine ; d'autres protéines intéressantes sont sensiblement similaires à ces protéines spécifiques, ou constituent des mutants de celles-ci, y compris des mutants non agrégants et des mutants possédant des caractéristiques d'oligomérisation modulées par comparaison avec le type sauvage. L'invention concerne aussi des fragments des acides nucléiques et les peptides codés par ceux-ci, ainsi que des anticorps dirigés contre les protéines en question et des cellules et organismes transgéniques. Cette protéine et ces compositions d'acide nucléique sont utiles dans diverses applications différentes. 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The proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein. Also of interest are proteins that are substantially similar to, or mutants of, the above specific proteins, including non-aggregating mutants and mutants with modulated oligomerization characteristics as compared to wild type. Also provided are fragments of the nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications, e.g., that include the subject nucleic acid compositions, are provided. L'invention concerne des compositions d'acide nucléique codant pour des chromoprotéines d'actinies, p. ex. condylactine, et des mutants fluorescents de celles-ci ; ainsi que les compositions polypeptidiques codées par ceux-ci. 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The proteins of interest are proteins that are colored and/or fluorescent, where this feature arises from the interaction of two or more residues of the protein. Also of interest are proteins that are substantially similar to, or mutants of, the above specific proteins, including non-aggregating mutants and mutants with modulated oligomerization characteristics as compared to wild type. Also provided are fragments of the nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications, e.g., that include the subject nucleic acid compositions, are provided. L'invention concerne des compositions d'acide nucléique codant pour des chromoprotéines d'actinies, p. ex. condylactine, et des mutants fluorescents de celles-ci ; ainsi que les compositions polypeptidiques codées par ceux-ci. Les protéines intéressantes sont des protéines colorées et/ou fluorescentes, cette caractéristique étant obtenue par l'interaction entre deux ou davantage de résidus de la protéine ; d'autres protéines intéressantes sont sensiblement similaires à ces protéines spécifiques, ou constituent des mutants de celles-ci, y compris des mutants non agrégants et des mutants possédant des caractéristiques d'oligomérisation modulées par comparaison avec le type sauvage. L'invention concerne aussi des fragments des acides nucléiques et les peptides codés par ceux-ci, ainsi que des anticorps dirigés contre les protéines en question et des cellules et organismes transgéniques. Cette protéine et ces compositions d'acide nucléique sont utiles dans diverses applications différentes. L'invention concerne également des trousses s'utilisant dans ces applications, p. ex. incluant lesdites compositions d'acide nucléique.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BEER
BIOCHEMISTRY
CARE OF BIRDS, FISHES, INSECTS
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NEW BREEDS OF ANIMALS
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
SPIRITS
TRAPPING
VINEGAR
WINE
title ANTHOZOA DERIVED CHROMOPROTEINS, FLUORESCENT MUTANTS THEREOF AND METHODS FOR USING THE SAME
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