ASSAY FOR DETECTING PRIMARY DNA DAMAGE
Die Erfindung betrifft ein Verfahren zum Nachweis von DNA-Schädigungen, wobei man das Auftreten einer spezifischen Wechselwirkung zwischen der zu untersuchenden DNA und DNA-Reparaturporteinen, insbesondere dem rekombinanten UvrA/UvrB-Protein von E.coli bestimmt. Weiterhin wird ein Reagenzienkit zur...
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| creator | KUHLMANN, JUERGEN FIRUS-PLASS, MARTINA BOESE, GUIDO MUELLER, OLIVER |
| description | Die Erfindung betrifft ein Verfahren zum Nachweis von DNA-Schädigungen, wobei man das Auftreten einer spezifischen Wechselwirkung zwischen der zu untersuchenden DNA und DNA-Reparaturporteinen, insbesondere dem rekombinanten UvrA/UvrB-Protein von E.coli bestimmt. Weiterhin wird ein Reagenzienkit zur Durchführung des Verfahrens offenbart.
The invention relates to a method for detecting DNA damage. According to said method, the occurrence of a specific interaction between the DNA to be examined and DNA repair proteins, especially the recombinant UvrA/UvrB protein of E.coli is determined. The invention also relates to a reagent kit for carrying out the method.
L'invention concerne un procédé pour déceler des endommagements d'ADN par la détermination d'une interaction spécifique entre l'ADN à analyser et les protéines de réparation d'ADN, notamment la protéine recombinante UvrA/UvrB de E.coli. L'invention concerne également un ensemble de réactifs à utiliser pour la mise en oeuvre de ce procédé. |
| format | Patent |
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The invention relates to a method for detecting DNA damage. According to said method, the occurrence of a specific interaction between the DNA to be examined and DNA repair proteins, especially the recombinant UvrA/UvrB protein of E.coli is determined. The invention also relates to a reagent kit for carrying out the method.
L'invention concerne un procédé pour déceler des endommagements d'ADN par la détermination d'une interaction spécifique entre l'ADN à analyser et les protéines de réparation d'ADN, notamment la protéine recombinante UvrA/UvrB de E.coli. L'invention concerne également un ensemble de réactifs à utiliser pour la mise en oeuvre de ce procédé.</description><edition>7</edition><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011227&DB=EPODOC&CC=WO&NR=0198780A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011227&DB=EPODOC&CC=WO&NR=0198780A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUHLMANN, JUERGEN</creatorcontrib><creatorcontrib>FIRUS-PLASS, MARTINA</creatorcontrib><creatorcontrib>BOESE, GUIDO</creatorcontrib><creatorcontrib>MUELLER, OLIVER</creatorcontrib><title>ASSAY FOR DETECTING PRIMARY DNA DAMAGE</title><description>Die Erfindung betrifft ein Verfahren zum Nachweis von DNA-Schädigungen, wobei man das Auftreten einer spezifischen Wechselwirkung zwischen der zu untersuchenden DNA und DNA-Reparaturporteinen, insbesondere dem rekombinanten UvrA/UvrB-Protein von E.coli bestimmt. Weiterhin wird ein Reagenzienkit zur Durchführung des Verfahrens offenbart.
The invention relates to a method for detecting DNA damage. According to said method, the occurrence of a specific interaction between the DNA to be examined and DNA repair proteins, especially the recombinant UvrA/UvrB protein of E.coli is determined. The invention also relates to a reagent kit for carrying out the method.
L'invention concerne un procédé pour déceler des endommagements d'ADN par la détermination d'une interaction spécifique entre l'ADN à analyser et les protéines de réparation d'ADN, notamment la protéine recombinante UvrA/UvrB de E.coli. L'invention concerne également un ensemble de réactifs à utiliser pour la mise en oeuvre de ce procédé.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBzDA52jFRw8w9ScHENcXUO8fRzVwgI8vR1DIpUcPFzVHBx9HV0d-VhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHh_gaGlhbmFgaORsZEKAEAaaIjEA</recordid><startdate>20011227</startdate><enddate>20011227</enddate><creator>KUHLMANN, JUERGEN</creator><creator>FIRUS-PLASS, MARTINA</creator><creator>BOESE, GUIDO</creator><creator>MUELLER, OLIVER</creator><scope>EVB</scope></search><sort><creationdate>20011227</creationdate><title>ASSAY FOR DETECTING PRIMARY DNA DAMAGE</title><author>KUHLMANN, JUERGEN ; FIRUS-PLASS, MARTINA ; BOESE, GUIDO ; MUELLER, OLIVER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO0198780A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2001</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KUHLMANN, JUERGEN</creatorcontrib><creatorcontrib>FIRUS-PLASS, MARTINA</creatorcontrib><creatorcontrib>BOESE, GUIDO</creatorcontrib><creatorcontrib>MUELLER, OLIVER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUHLMANN, JUERGEN</au><au>FIRUS-PLASS, MARTINA</au><au>BOESE, GUIDO</au><au>MUELLER, OLIVER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ASSAY FOR DETECTING PRIMARY DNA DAMAGE</title><date>2001-12-27</date><risdate>2001</risdate><abstract>Die Erfindung betrifft ein Verfahren zum Nachweis von DNA-Schädigungen, wobei man das Auftreten einer spezifischen Wechselwirkung zwischen der zu untersuchenden DNA und DNA-Reparaturporteinen, insbesondere dem rekombinanten UvrA/UvrB-Protein von E.coli bestimmt. Weiterhin wird ein Reagenzienkit zur Durchführung des Verfahrens offenbart.
The invention relates to a method for detecting DNA damage. According to said method, the occurrence of a specific interaction between the DNA to be examined and DNA repair proteins, especially the recombinant UvrA/UvrB protein of E.coli is determined. The invention also relates to a reagent kit for carrying out the method.
L'invention concerne un procédé pour déceler des endommagements d'ADN par la détermination d'une interaction spécifique entre l'ADN à analyser et les protéines de réparation d'ADN, notamment la protéine recombinante UvrA/UvrB de E.coli. L'invention concerne également un ensemble de réactifs à utiliser pour la mise en oeuvre de ce procédé.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | ASSAY FOR DETECTING PRIMARY DNA DAMAGE |
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