VACCINE FOR CONGENITAL TREMORS IN PIGS
The invention is based on the cloning of porcine circovirus (PCV) strains from pigs with congenital tremors. These results provide a first step for the development of diagnostic and therapeutic applications for congenital tremors in a pig. The diagnostic method comprises determining whether the pig...
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| creator | KIUPEL, MATTI CHOI, JIWON MITTAL, SURESH, K STEVENSON, GREGORY, W KANITZ, CHARLES, L |
| description | The invention is based on the cloning of porcine circovirus (PCV) strains from pigs with congenital tremors. These results provide a first step for the development of diagnostic and therapeutic applications for congenital tremors in a pig. The diagnostic method comprises determining whether the pig has been infected by a porcine circovirus strain of type 1 or type 2. The invention further provides a method for the prevention or treatment of congenital tremors in a pig, which method comprises administering to the pig an effective amount of an immunogenic PCV 1 or PCV 2 polypeptide or of a nucleic acid encoding this polypeptide. Another subject of the invention is the new PCV nucleic acid sequences identified by the inventors and the polypeptides encoded by these sequences, as well as the new PCV isolates and immunogenic preparations thereof.
La présente invention repose sur le clonage de souches du circovirus porcin (CVP) provenant de porcs atteints de tremblements congénitaux. L'invention constitue une première étape dans la mise au point d'applications diagnostiques et thérapeutiques destinées à traiter les tremblements congénitaux chez les porcs. Le procédé diagnostique de l'invention consiste à déterminer si le porc a été infecté par une souche de circovirus porcin de type 1 ou de type 2. L'invention concerne également un procédé permettant de traiter ou de prévenir les tremblements congénitaux chez le porc, selon lequel on administre au porc une quantité efficace d'un polypeptide immunogène de CVP1 ou CVP2 ou d'un acide nucléique codant ledit polypeptide. L'invention concerne également de nouvelles séquences d'acide nucléique du CVP qui ont été identifiées par les inventeurs et les polypeptides codés par ces séquences, ainsi que de nouveaux isolats de CVP et des préparations immunogènes fabriquées à partir de ces derniers. |
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La présente invention repose sur le clonage de souches du circovirus porcin (CVP) provenant de porcs atteints de tremblements congénitaux. L'invention constitue une première étape dans la mise au point d'applications diagnostiques et thérapeutiques destinées à traiter les tremblements congénitaux chez les porcs. Le procédé diagnostique de l'invention consiste à déterminer si le porc a été infecté par une souche de circovirus porcin de type 1 ou de type 2. L'invention concerne également un procédé permettant de traiter ou de prévenir les tremblements congénitaux chez le porc, selon lequel on administre au porc une quantité efficace d'un polypeptide immunogène de CVP1 ou CVP2 ou d'un acide nucléique codant ledit polypeptide. L'invention concerne également de nouvelles séquences d'acide nucléique du CVP qui ont été identifiées par les inventeurs et les polypeptides codés par ces séquences, ainsi que de nouveaux isolats de CVP et des préparations immunogènes fabriquées à partir de ces derniers.</description><edition>7</edition><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011220&DB=EPODOC&CC=WO&NR=0196377A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011220&DB=EPODOC&CC=WO&NR=0196377A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIUPEL, MATTI</creatorcontrib><creatorcontrib>CHOI, JIWON</creatorcontrib><creatorcontrib>MITTAL, SURESH, K</creatorcontrib><creatorcontrib>STEVENSON, GREGORY, W</creatorcontrib><creatorcontrib>KANITZ, CHARLES, L</creatorcontrib><title>VACCINE FOR CONGENITAL TREMORS IN PIGS</title><description>The invention is based on the cloning of porcine circovirus (PCV) strains from pigs with congenital tremors. These results provide a first step for the development of diagnostic and therapeutic applications for congenital tremors in a pig. The diagnostic method comprises determining whether the pig has been infected by a porcine circovirus strain of type 1 or type 2. The invention further provides a method for the prevention or treatment of congenital tremors in a pig, which method comprises administering to the pig an effective amount of an immunogenic PCV 1 or PCV 2 polypeptide or of a nucleic acid encoding this polypeptide. Another subject of the invention is the new PCV nucleic acid sequences identified by the inventors and the polypeptides encoded by these sequences, as well as the new PCV isolates and immunogenic preparations thereof.
La présente invention repose sur le clonage de souches du circovirus porcin (CVP) provenant de porcs atteints de tremblements congénitaux. L'invention constitue une première étape dans la mise au point d'applications diagnostiques et thérapeutiques destinées à traiter les tremblements congénitaux chez les porcs. Le procédé diagnostique de l'invention consiste à déterminer si le porc a été infecté par une souche de circovirus porcin de type 1 ou de type 2. L'invention concerne également un procédé permettant de traiter ou de prévenir les tremblements congénitaux chez le porc, selon lequel on administre au porc une quantité efficace d'un polypeptide immunogène de CVP1 ou CVP2 ou d'un acide nucléique codant ledit polypeptide. L'invention concerne également de nouvelles séquences d'acide nucléique du CVP qui ont été identifiées par les inventeurs et les polypeptides codés par ces séquences, ainsi que de nouveaux isolats de CVP et des préparations immunogènes fabriquées à partir de ces derniers.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFALc3R29vRzVXDzD1Jw9vdzd_XzDHH0UQgJcvX1DwpW8PRTCPB0D-ZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHh_gaGlmbG5uaORsZEKAEAdYYjNQ</recordid><startdate>20011220</startdate><enddate>20011220</enddate><creator>KIUPEL, MATTI</creator><creator>CHOI, JIWON</creator><creator>MITTAL, SURESH, K</creator><creator>STEVENSON, GREGORY, W</creator><creator>KANITZ, CHARLES, L</creator><scope>EVB</scope></search><sort><creationdate>20011220</creationdate><title>VACCINE FOR CONGENITAL TREMORS IN PIGS</title><author>KIUPEL, MATTI ; CHOI, JIWON ; MITTAL, SURESH, K ; STEVENSON, GREGORY, W ; KANITZ, CHARLES, L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO0196377A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2001</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KIUPEL, MATTI</creatorcontrib><creatorcontrib>CHOI, JIWON</creatorcontrib><creatorcontrib>MITTAL, SURESH, K</creatorcontrib><creatorcontrib>STEVENSON, GREGORY, W</creatorcontrib><creatorcontrib>KANITZ, CHARLES, L</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KIUPEL, MATTI</au><au>CHOI, JIWON</au><au>MITTAL, SURESH, K</au><au>STEVENSON, GREGORY, W</au><au>KANITZ, CHARLES, L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>VACCINE FOR CONGENITAL TREMORS IN PIGS</title><date>2001-12-20</date><risdate>2001</risdate><abstract>The invention is based on the cloning of porcine circovirus (PCV) strains from pigs with congenital tremors. These results provide a first step for the development of diagnostic and therapeutic applications for congenital tremors in a pig. The diagnostic method comprises determining whether the pig has been infected by a porcine circovirus strain of type 1 or type 2. The invention further provides a method for the prevention or treatment of congenital tremors in a pig, which method comprises administering to the pig an effective amount of an immunogenic PCV 1 or PCV 2 polypeptide or of a nucleic acid encoding this polypeptide. Another subject of the invention is the new PCV nucleic acid sequences identified by the inventors and the polypeptides encoded by these sequences, as well as the new PCV isolates and immunogenic preparations thereof.
La présente invention repose sur le clonage de souches du circovirus porcin (CVP) provenant de porcs atteints de tremblements congénitaux. L'invention constitue une première étape dans la mise au point d'applications diagnostiques et thérapeutiques destinées à traiter les tremblements congénitaux chez les porcs. Le procédé diagnostique de l'invention consiste à déterminer si le porc a été infecté par une souche de circovirus porcin de type 1 ou de type 2. L'invention concerne également un procédé permettant de traiter ou de prévenir les tremblements congénitaux chez le porc, selon lequel on administre au porc une quantité efficace d'un polypeptide immunogène de CVP1 ou CVP2 ou d'un acide nucléique codant ledit polypeptide. L'invention concerne également de nouvelles séquences d'acide nucléique du CVP qui ont été identifiées par les inventeurs et les polypeptides codés par ces séquences, ainsi que de nouveaux isolats de CVP et des préparations immunogènes fabriquées à partir de ces derniers.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE |
| title | VACCINE FOR CONGENITAL TREMORS IN PIGS |
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