METHODS AND MATERIALS RELATING TO STEM CELL FACTOR-LIKE (SCF-LIKE) POLYPEPTIDES AND POLYNUCLEOTIDES

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted SCF-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from human bone ma...

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Hauptverfasser: KUO, CHIAOYON, BOYLE, BRYAN, J, FUNK, WALTER, ARTERBURN, MATTHEW, C
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creator KUO, CHIAOYON
BOYLE, BRYAN, J
FUNK, WALTER
ARTERBURN, MATTHEW, C
description The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted SCF-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries prepared from human bone marrow (Clontech), fetal kidney (Clontech), and fetal muscle (Invitrogen) mRNAs (Clontech)(SEQ ID NO: 1). Other aspects of the invention include vectors containing processes for producing novel human secreted SCF-like polypeptides, and antibodies specific for such polypeptides. L'invention concerne des nouveaux polynucléotides et des polypeptides codés par de tels polynucléotides, ainsi que des mutants ou variants de ceux-ci correspondant à un nouveau polypeptide humain sécrété du type FCS. Ces polynucléotides comprennent des séquences d'acide nucléique isolées à partir des banques de ADNc préparées à partir de moelle osseuse (Clontech), de foie de foetus (Clontech) et de l'ARNm de muscle de foetus (Invitrogen) (Clontech) (SEQ ID NO: 1) humains. D'autres aspects de l'invention concernent des vecteurs renfermant des procédés de production des nouveaux polypeptides humains sécrétés du type FCS, ainsi que des anticorps spécifiques de ces polypeptides.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title METHODS AND MATERIALS RELATING TO STEM CELL FACTOR-LIKE (SCF-LIKE) POLYPEPTIDES AND POLYNUCLEOTIDES
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