SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS
Certain novel spiropiperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activa...
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| creator | NARGUND, RAVI, P PALUCKI, BRENDA, L |
| description | Certain novel spiropiperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
Selon l'invention, certains nouveaux dérivés de spiropipéridine sont des agonistes du (des) récepteur(s) de la mélanocortine humaine et, en particulier, des agonistes sélectifs du récepteur de la mélanocortine 4 humaine (MC-4R). Ils sont donc utiles pour le traitement, le contrôle ou la prévention de maladies et de troubles sensibles à l'activation de MC-4R, tels que l'obésité, le diabète, la dysfonction sexuelle (y compris la dysérection et la dysfonction sexuelle chez la femme). |
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Selon l'invention, certains nouveaux dérivés de spiropipéridine sont des agonistes du (des) récepteur(s) de la mélanocortine humaine et, en particulier, des agonistes sélectifs du récepteur de la mélanocortine 4 humaine (MC-4R). Ils sont donc utiles pour le traitement, le contrôle ou la prévention de maladies et de troubles sensibles à l'activation de MC-4R, tels que l'obésité, le diabète, la dysfonction sexuelle (y compris la dysérection et la dysfonction sexuelle chez la femme).</description><edition>7</edition><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010927&DB=EPODOC&CC=WO&NR=0170337A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010927&DB=EPODOC&CC=WO&NR=0170337A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NARGUND, RAVI, P</creatorcontrib><creatorcontrib>PALUCKI, BRENDA, L</creatorcontrib><title>SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS</title><description>Certain novel spiropiperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
Selon l'invention, certains nouveaux dérivés de spiropipéridine sont des agonistes du (des) récepteur(s) de la mélanocortine humaine et, en particulier, des agonistes sélectifs du récepteur de la mélanocortine 4 humaine (MC-4R). Ils sont donc utiles pour le traitement, le contrôle ou la prévention de maladies et de troubles sensibles à l'activation de MC-4R, tels que l'obésité, le diabète, la dysfonction sexuelle (y compris la dysérection et la dysfonction sexuelle chez la femme).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLANDvAM8g_wDHAN8nTx9HNVcAEywhxDPMNcgxUcgxV8XX0c_fyd_YNCPP0UglydXQNC_IMUHN39_TyDQ4J5GFjTEnOKU3mhNDeDgptriLOHbmpBfnxqcUFicmpeakl8uL-BobmBsbG5o6ExEUoAKLMqHw</recordid><startdate>20010927</startdate><enddate>20010927</enddate><creator>NARGUND, RAVI, P</creator><creator>PALUCKI, BRENDA, L</creator><scope>EVB</scope></search><sort><creationdate>20010927</creationdate><title>SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS</title><author>NARGUND, RAVI, P ; PALUCKI, BRENDA, L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO0170337A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2001</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>NARGUND, RAVI, P</creatorcontrib><creatorcontrib>PALUCKI, BRENDA, L</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NARGUND, RAVI, P</au><au>PALUCKI, BRENDA, L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS</title><date>2001-09-27</date><risdate>2001</risdate><abstract>Certain novel spiropiperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
Selon l'invention, certains nouveaux dérivés de spiropipéridine sont des agonistes du (des) récepteur(s) de la mélanocortine humaine et, en particulier, des agonistes sélectifs du récepteur de la mélanocortine 4 humaine (MC-4R). Ils sont donc utiles pour le traitement, le contrôle ou la prévention de maladies et de troubles sensibles à l'activation de MC-4R, tels que l'obésité, le diabète, la dysfonction sexuelle (y compris la dysérection et la dysfonction sexuelle chez la femme).</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS |
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