PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING
Described herein is a physiologically balanced, ionized, acidic solution, typically prepared by the electrolysis of a solution comprising a mixture of inorganic salts in physiologically balanced proportions. This invention also relates to the use of the solutions. A mixture of inorganic salts and, o...
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| description | Described herein is a physiologically balanced, ionized, acidic solution, typically prepared by the electrolysis of a solution comprising a mixture of inorganic salts in physiologically balanced proportions. This invention also relates to the use of the solutions. A mixture of inorganic salts and, optionally minerals, (such as metallic elements) is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises halide salts of sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide. A typical electrolyzed solution of the invention has a pH within the range of about 2 to about 6, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and a titratable halide content within the range of about 10 ppm to about 100 ppm. The pH of the electrolyzed, chlorine-comprising solution is typically lowered to about 6 or less, giving the solution bactericidal, fungicidal, and sporicidal properties. The composition is nontoxid and is useful in any application in which antimicrobial properties are desirable. The composition can be incorporated into a bandage or wound dressing, preferably, a specialized bandage which can be opened and closed, and through which topical treatment materials such as the solution of the present invention may be applied.
L'invention concerne une solution acide ionisée physiologiquement équilibrée. Cette solution est généralement préparée par électrolyse d'une solution contenant un mélange de sels inorganiques dans des proportions physiologiquement équilibrées. L'invention concerne également une méthode d'utilisation de ces solutions. Un mélange de sels inorganiques, et éventuellement de minéraux (tels que des éléments métalliques et non par limitation), est utilisé pour imiter la concentration et le mélange électrolytique du liquide organique dans un état isotonique. La solution comprend généralement des sels de sodium halogénés, du potassium, du calcium et d'autres cations. L'halogénure est généralement fluor, chlore, bromure ou iodure. Selon l'invention, une solution électrolytique typique présente un pH compris entre environ 2 et 6, un potentiel d'oxydo-réduction compris entre environ +600 mV et +1200 mV, et une teneur en halogénure de titration comprise entre environ 10 et 100 mg/l. Le pH de la solution chlorée électrolytique peut être réduit à environ 6 ou moins, ce qui confère à la solution |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO0154704A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO0154704A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO0154704A13</originalsourceid><addsrcrecordid>eNrjZIgO8IgM9vT38Xf3dHb08YlUcHL0cfRzdnXRUfD09_OMAjEcnT1dPJ0Vgv19QkOAggqOfi4Kvq4hHv4uIH2RCm7-QQqhwa4Knn4K4f6hQEkPV0cfTz93HgbWtMSc4lReKM3NoODmGuLsoZtakB-fWlyQmJyal1oSH-5vYGhqYm5g4mhoTIQSABV3MY4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING</title><source>esp@cenet</source><creator>BERNARD, SUZANNE, M ; NAJAFI, RAMIN</creator><creatorcontrib>BERNARD, SUZANNE, M ; NAJAFI, RAMIN</creatorcontrib><description>Described herein is a physiologically balanced, ionized, acidic solution, typically prepared by the electrolysis of a solution comprising a mixture of inorganic salts in physiologically balanced proportions. This invention also relates to the use of the solutions. A mixture of inorganic salts and, optionally minerals, (such as metallic elements) is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises halide salts of sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide. A typical electrolyzed solution of the invention has a pH within the range of about 2 to about 6, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and a titratable halide content within the range of about 10 ppm to about 100 ppm. The pH of the electrolyzed, chlorine-comprising solution is typically lowered to about 6 or less, giving the solution bactericidal, fungicidal, and sporicidal properties. The composition is nontoxid and is useful in any application in which antimicrobial properties are desirable. The composition can be incorporated into a bandage or wound dressing, preferably, a specialized bandage which can be opened and closed, and through which topical treatment materials such as the solution of the present invention may be applied.
L'invention concerne une solution acide ionisée physiologiquement équilibrée. Cette solution est généralement préparée par électrolyse d'une solution contenant un mélange de sels inorganiques dans des proportions physiologiquement équilibrées. L'invention concerne également une méthode d'utilisation de ces solutions. Un mélange de sels inorganiques, et éventuellement de minéraux (tels que des éléments métalliques et non par limitation), est utilisé pour imiter la concentration et le mélange électrolytique du liquide organique dans un état isotonique. La solution comprend généralement des sels de sodium halogénés, du potassium, du calcium et d'autres cations. L'halogénure est généralement fluor, chlore, bromure ou iodure. Selon l'invention, une solution électrolytique typique présente un pH compris entre environ 2 et 6, un potentiel d'oxydo-réduction compris entre environ +600 mV et +1200 mV, et une teneur en halogénure de titration comprise entre environ 10 et 100 mg/l. Le pH de la solution chlorée électrolytique peut être réduit à environ 6 ou moins, ce qui confère à la solution des propriétés bactéricides, fongicides et sporicides. La composition de l'invention est non toxique et utile dans toute application dans laquelle des propriétés antimicrobiennes sont désirées. Cette composition peut être incorporée dans un matériel de bandage ou pansement, de préférence un matériel de bandage spécialisé pouvant être ouvert ou fermé, et au moyen duquel des substances de traitement topique, telles que la solution de l'invention, peuvent être appliquées.</description><edition>7</edition><language>eng ; fre</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROSTHESES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010802&DB=EPODOC&CC=WO&NR=0154704A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010802&DB=EPODOC&CC=WO&NR=0154704A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BERNARD, SUZANNE, M</creatorcontrib><creatorcontrib>NAJAFI, RAMIN</creatorcontrib><title>PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING</title><description>Described herein is a physiologically balanced, ionized, acidic solution, typically prepared by the electrolysis of a solution comprising a mixture of inorganic salts in physiologically balanced proportions. This invention also relates to the use of the solutions. A mixture of inorganic salts and, optionally minerals, (such as metallic elements) is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises halide salts of sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide. A typical electrolyzed solution of the invention has a pH within the range of about 2 to about 6, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and a titratable halide content within the range of about 10 ppm to about 100 ppm. The pH of the electrolyzed, chlorine-comprising solution is typically lowered to about 6 or less, giving the solution bactericidal, fungicidal, and sporicidal properties. The composition is nontoxid and is useful in any application in which antimicrobial properties are desirable. The composition can be incorporated into a bandage or wound dressing, preferably, a specialized bandage which can be opened and closed, and through which topical treatment materials such as the solution of the present invention may be applied.
L'invention concerne une solution acide ionisée physiologiquement équilibrée. Cette solution est généralement préparée par électrolyse d'une solution contenant un mélange de sels inorganiques dans des proportions physiologiquement équilibrées. L'invention concerne également une méthode d'utilisation de ces solutions. Un mélange de sels inorganiques, et éventuellement de minéraux (tels que des éléments métalliques et non par limitation), est utilisé pour imiter la concentration et le mélange électrolytique du liquide organique dans un état isotonique. La solution comprend généralement des sels de sodium halogénés, du potassium, du calcium et d'autres cations. L'halogénure est généralement fluor, chlore, bromure ou iodure. Selon l'invention, une solution électrolytique typique présente un pH compris entre environ 2 et 6, un potentiel d'oxydo-réduction compris entre environ +600 mV et +1200 mV, et une teneur en halogénure de titration comprise entre environ 10 et 100 mg/l. Le pH de la solution chlorée électrolytique peut être réduit à environ 6 ou moins, ce qui confère à la solution des propriétés bactéricides, fongicides et sporicides. La composition de l'invention est non toxique et utile dans toute application dans laquelle des propriétés antimicrobiennes sont désirées. Cette composition peut être incorporée dans un matériel de bandage ou pansement, de préférence un matériel de bandage spécialisé pouvant être ouvert ou fermé, et au moyen duquel des substances de traitement topique, telles que la solution de l'invention, peuvent être appliquées.</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>CHEMISTRY</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROSTHESES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIgO8IgM9vT38Xf3dHb08YlUcHL0cfRzdnXRUfD09_OMAjEcnT1dPJ0Vgv19QkOAggqOfi4Kvq4hHv4uIH2RCm7-QQqhwa4Knn4K4f6hQEkPV0cfTz93HgbWtMSc4lReKM3NoODmGuLsoZtakB-fWlyQmJyal1oSH-5vYGhqYm5g4mhoTIQSABV3MY4</recordid><startdate>20010802</startdate><enddate>20010802</enddate><creator>BERNARD, SUZANNE, M</creator><creator>NAJAFI, RAMIN</creator><scope>EVB</scope></search><sort><creationdate>20010802</creationdate><title>PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING</title><author>BERNARD, SUZANNE, M ; NAJAFI, RAMIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO0154704A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2001</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>CHEMISTRY</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROSTHESES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>BERNARD, SUZANNE, M</creatorcontrib><creatorcontrib>NAJAFI, RAMIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BERNARD, SUZANNE, M</au><au>NAJAFI, RAMIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING</title><date>2001-08-02</date><risdate>2001</risdate><abstract>Described herein is a physiologically balanced, ionized, acidic solution, typically prepared by the electrolysis of a solution comprising a mixture of inorganic salts in physiologically balanced proportions. This invention also relates to the use of the solutions. A mixture of inorganic salts and, optionally minerals, (such as metallic elements) is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises halide salts of sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide. A typical electrolyzed solution of the invention has a pH within the range of about 2 to about 6, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and a titratable halide content within the range of about 10 ppm to about 100 ppm. The pH of the electrolyzed, chlorine-comprising solution is typically lowered to about 6 or less, giving the solution bactericidal, fungicidal, and sporicidal properties. The composition is nontoxid and is useful in any application in which antimicrobial properties are desirable. The composition can be incorporated into a bandage or wound dressing, preferably, a specialized bandage which can be opened and closed, and through which topical treatment materials such as the solution of the present invention may be applied.
L'invention concerne une solution acide ionisée physiologiquement équilibrée. Cette solution est généralement préparée par électrolyse d'une solution contenant un mélange de sels inorganiques dans des proportions physiologiquement équilibrées. L'invention concerne également une méthode d'utilisation de ces solutions. Un mélange de sels inorganiques, et éventuellement de minéraux (tels que des éléments métalliques et non par limitation), est utilisé pour imiter la concentration et le mélange électrolytique du liquide organique dans un état isotonique. La solution comprend généralement des sels de sodium halogénés, du potassium, du calcium et d'autres cations. L'halogénure est généralement fluor, chlore, bromure ou iodure. Selon l'invention, une solution électrolytique typique présente un pH compris entre environ 2 et 6, un potentiel d'oxydo-réduction compris entre environ +600 mV et +1200 mV, et une teneur en halogénure de titration comprise entre environ 10 et 100 mg/l. Le pH de la solution chlorée électrolytique peut être réduit à environ 6 ou moins, ce qui confère à la solution des propriétés bactéricides, fongicides et sporicides. La composition de l'invention est non toxique et utile dans toute application dans laquelle des propriétés antimicrobiennes sont désirées. Cette composition peut être incorporée dans un matériel de bandage ou pansement, de préférence un matériel de bandage spécialisé pouvant être ouvert ou fermé, et au moyen duquel des substances de traitement topique, telles que la solution de l'invention, peuvent être appliquées.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROSTHESES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE TREATMENT OR PROTECTION OF EYES OR EARS |
| title | PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING |
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