GENES ENCODING ABC1 PARALOGS AND THE POLYPEPTIDES DERIVED THEREFROM

The present invention relates to three novel genes and polypeptides derived therefrom encoding "PD-ABC" proteins. The invention also describes methods for using the novel gene and polypeptides in the detection of genetic deletions of the gene, subcellular localization of the polypeptide, b...

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Hauptverfasser: WANG, MINGHAN, JOHNS, MARGARET, ANN, TAFURI, SHERRIE, RAE
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creator WANG, MINGHAN
JOHNS, MARGARET, ANN
TAFURI, SHERRIE, RAE
description The present invention relates to three novel genes and polypeptides derived therefrom encoding "PD-ABC" proteins. The invention also describes methods for using the novel gene and polypeptides in the detection of genetic deletions of the gene, subcellular localization of the polypeptide, binding assays in connection with the chemical databases, gene therapy, and identification of chemicals which may be used in the therapeutic treatment of PD-ABC-mediated diseases. L'invention concerne trois nouveaux gènes et des polypeptides dérivés de ceux-ci, qui codent pour des protéines de /= . L'invention concerne également des procédés d'utilisation du nouveau gène et des polypeptides pour détecter des délétions génétiques du gène, à des fins de localisation sous-cellulaire du polypeptide, dans des techniques de titrage par liaison associées à des bases de données chimiques, en thérapie génique et pour identifier des produits chimiques pouvant être utilisés dans le traitement thérapeutique de maladies dépendant de PD-ABC.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title GENES ENCODING ABC1 PARALOGS AND THE POLYPEPTIDES DERIVED THEREFROM
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