MULTILAYERED MICROFLUIDIC DEVICES FOR ANALYTE REACTIONS

The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices. In preferred aspects, the devices are fabricated using ceramic multilayer technology to form devices in which parallel, independently controlled molecular reactions, such as nucleic a...

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Bibliographische Detailangaben
Hauptverfasser:	MCGARRY, MARK, W, TUGGLE, TODD, CHAN, TONY, HAWKINS, GEORGE, HUANG, RONG-FONG, KAHN, PETER, GRODZINSKI, PIOTR, MARRERO, ROBERT, BURDON, JEREMY, W, FOLEY, BARBARA, YU, HUINAN, BRISCOE, CYNTHIA, G
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY BLASTING CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OFGENERAL APPLICATION ENZYMOLOGY HEAT EXCHANGE IN GENERAL HEATING INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES LIGHTING MEASURING MECHANICAL ENGINEERING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING THEIR RELEVANT APPARATUS TRANSPORTING VINEGAR WEAPONS WINE
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Beschreibung
Zusammenfassung:	The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices. In preferred aspects, the devices are fabricated using ceramic multilayer technology to form devices in which parallel, independently controlled molecular reactions, such as nucleic acid amplification reactions including the polymerase chain reaction (PCR) can be performed. Additionally, the devices can include and comprise micro-gas chromatographs similarly fabricated from ceramics. L'invention concerne des procédés et des appareils servant à réaliser des analyses, notamment des dispositifs microfluidiques. Selon des aspects préférés, les dispositifs sont fabriqués au moyen d'une technique multicouches de céramique destinée à constituer des dispositifs dans lesquels on peut réaliser des réactions moléculaires parallèles, régulées indépendamment, telles que des réactions d'amplification d'acides nucléiques comprenant la réaction en chaîne de la polymérase (PCR). En outre, les dispositifs peuvent inclure et comprendre des micro chromatographes en phase gazeuse, fabriqués de manière similaire à partir de céramique.