NPY ANTAGONISTS: SPIROISOQUINOLINONE DERIVATIVES
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of spiroisoquinolinone derivatives of Formula (I). As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and...
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| creator | POINDEXTER, GRAHAM, S ANTAL, ILDIKO GIUPPONI, LEAH, M BRUCE, MARC STOFFEL, ROBERT, H |
| description | A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of spiroisoquinolinone derivatives of Formula (I). As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
L'invention concerne une série d'antagonistes non peptidergiques des neuropeptides Y (NPY) synthétisés et comprenant des dérivés de spiroisoquinolinone de formule (I). En tant qu'antagonistes de comportement alimentaire induit par les neuropeptides Y, on peut s'attendre que ces composés et les produits analogues agissent comme des agents anorexigènes efficaces en favorisant la perte de poids et le traitement des troubles alimentaires. |
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L'invention concerne une série d'antagonistes non peptidergiques des neuropeptides Y (NPY) synthétisés et comprenant des dérivés de spiroisoquinolinone de formule (I). En tant qu'antagonistes de comportement alimentaire induit par les neuropeptides Y, on peut s'attendre que ces composés et les produits analogues agissent comme des agents anorexigènes efficaces en favorisant la perte de poids et le traitement des troubles alimentaires.</description><edition>7</edition><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010301&DB=EPODOC&CC=WO&NR=0113917A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010301&DB=EPODOC&CC=WO&NR=0113917A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>POINDEXTER, GRAHAM, S</creatorcontrib><creatorcontrib>ANTAL, ILDIKO</creatorcontrib><creatorcontrib>GIUPPONI, LEAH, M</creatorcontrib><creatorcontrib>BRUCE, MARC</creatorcontrib><creatorcontrib>STOFFEL, ROBERT, H</creatorcontrib><title>NPY ANTAGONISTS: SPIROISOQUINOLINONE DERIVATIVES</title><description>A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of spiroisoquinolinone derivatives of Formula (I). As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
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L'invention concerne une série d'antagonistes non peptidergiques des neuropeptides Y (NPY) synthétisés et comprenant des dérivés de spiroisoquinolinone de formule (I). En tant qu'antagonistes de comportement alimentaire induit par les neuropeptides Y, on peut s'attendre que ces composés et les produits analogues agissent comme des agents anorexigènes efficaces en favorisant la perte de poids et le traitement des troubles alimentaires.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NPY ANTAGONISTS: SPIROISOQUINOLINONE DERIVATIVES |
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