ANTAGONISTAS DEL RECEPTOR CRTH2 BASADOS EN INDOL

Se desvelan compuestos de Fórmula (I), que son útiles como antagonistas de los receptores CRTH2. También se desvelan composiciones farmacéuticas que contienen compuestos de Fórmula(I) y el uso de compuestos de Fórmula (I) para tratar enfermedades o trastornos que son sensibles a la inhibición de la...

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Hauptverfasser: KRISTIN MARIE JANZ, KAILA NEELU, MICHAEL DENNIS LOWE, SAIAH EDDINE, TAREK SUHAYL MANSOUR, HUANG ADRIAN, ALESSANDRO FABIO MORETTO, JENNIFER ROMANIC THOMASON, CARA MARGARET MAY WILLIAMS, BRUCE CHRISTOPHER FOLLOWS
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creator KRISTIN MARIE JANZ
KAILA NEELU
MICHAEL DENNIS LOWE
SAIAH EDDINE
TAREK SUHAYL MANSOUR
HUANG ADRIAN
ALESSANDRO FABIO MORETTO
JENNIFER ROMANIC THOMASON
CARA MARGARET MAY WILLIAMS
BRUCE CHRISTOPHER FOLLOWS
description Se desvelan compuestos de Fórmula (I), que son útiles como antagonistas de los receptores CRTH2. También se desvelan composiciones farmacéuticas que contienen compuestos de Fórmula(I) y el uso de compuestos de Fórmula (I) para tratar enfermedades o trastornos que son sensibles a la inhibición de la unión de ligandos endógenos al receptorCRTH2. También se describen procedimientos para preparar y usar estos compuestos. Disclosed are compounds of Formula (I): which are useful as antagonists of the CRTH2 receptors. Pharmaceutical compositions containing compounds of Formula (I) and the use of compounds of Formula (I) to treat diseases or disorders that are responsive to inhibition of the binding of endogenous ligands to the CRTH2 receptor are also disclosed. Methods for preparing and using these compounds are further described.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTAGONISTAS DEL RECEPTOR CRTH2 BASADOS EN INDOL
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