DERIVADOS DE ADENINAS, COMPOSICIONES FARMACÉUTICAS CONTENIÉNDOLOS, PROCEDIMIENTOS DE PREPARACIÓN Y APLICACIONES
La presente invención proporciona compuestos de fórmula donde R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R y R2 son como se define en la memoria descriptiva, a procesos para su preparación, a composiciones farmacéuticas que los contienen y a su uso en terapia. Se trata de compuestos 9-sustituidos-8-oxoadenin...
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| creator | STEPHEN BROUGH KAMALDEEP CHOHAN KEI NORIMURA SHINGO TOJO PHILIP ABBOTT STEPHEN THOM ROGER VICTOR BONNERT YOSHIAKI ISOBE THOMAS MCINALLY |
| description | La presente invención proporciona compuestos de fórmula donde R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R y R2 son como se define en la memoria descriptiva, a procesos para su preparación, a composiciones farmacéuticas que los contienen y a su uso en terapia. Se trata de compuestos 9-sustituidos-8-oxoadenina con propiedades inmuno modulantes que actúan vía TLR7 útiles para el tratamiento de enfermedades virales, alérgicas y cáncer.
The present invention provides compounds of formula (I) wherein R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. |
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The present invention provides compounds of formula (I) wherein R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070430&DB=EPODOC&CC=UY&NR=29803A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070430&DB=EPODOC&CC=UY&NR=29803A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>STEPHEN BROUGH</creatorcontrib><creatorcontrib>KAMALDEEP CHOHAN</creatorcontrib><creatorcontrib>KEI NORIMURA</creatorcontrib><creatorcontrib>SHINGO TOJO</creatorcontrib><creatorcontrib>PHILIP ABBOTT</creatorcontrib><creatorcontrib>STEPHEN THOM</creatorcontrib><creatorcontrib>ROGER VICTOR BONNERT</creatorcontrib><creatorcontrib>YOSHIAKI ISOBE</creatorcontrib><creatorcontrib>THOMAS MCINALLY</creatorcontrib><title>DERIVADOS DE ADENINAS, COMPOSICIONES FARMACÉUTICAS CONTENIÉNDOLOS, PROCEDIMIENTOS DE PREPARACIÓN Y APLICACIONES</title><description>La presente invención proporciona compuestos de fórmula donde R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R y R2 son como se define en la memoria descriptiva, a procesos para su preparación, a composiciones farmacéuticas que los contienen y a su uso en terapia. Se trata de compuestos 9-sustituidos-8-oxoadenina con propiedades inmuno modulantes que actúan vía TLR7 útiles para el tratamiento de enfermedades virales, alérgicas y cáncer.
The present invention provides compounds of formula (I) wherein R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjLEKwjAURbs4iPoLkg9QULvo-Ehe8UHzEpJU6FSKxEm0WH-is5_UHzNQd6c73HPOPHspdHQBZbxQKEAhE4PfCGm0NZ4kGUYvCnAa5DhUgST4dHJI4DiwMqVJtHVGoiJNyGEqWYcWHEgaPyxqAbZM5lRbZrNbe-_j6reLbF1gkOdt7J5N7Lv2Gh_x3VT14XTc5bDP_wJfQKQ50g</recordid><startdate>20070430</startdate><enddate>20070430</enddate><creator>STEPHEN BROUGH</creator><creator>KAMALDEEP CHOHAN</creator><creator>KEI NORIMURA</creator><creator>SHINGO TOJO</creator><creator>PHILIP ABBOTT</creator><creator>STEPHEN THOM</creator><creator>ROGER VICTOR BONNERT</creator><creator>YOSHIAKI ISOBE</creator><creator>THOMAS MCINALLY</creator><scope>EVB</scope></search><sort><creationdate>20070430</creationdate><title>DERIVADOS DE ADENINAS, COMPOSICIONES FARMACÉUTICAS CONTENIÉNDOLOS, PROCEDIMIENTOS DE PREPARACIÓN Y APLICACIONES</title><author>STEPHEN BROUGH ; KAMALDEEP CHOHAN ; KEI NORIMURA ; SHINGO TOJO ; PHILIP ABBOTT ; STEPHEN THOM ; ROGER VICTOR BONNERT ; YOSHIAKI ISOBE ; THOMAS MCINALLY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_UY29803A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2007</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>STEPHEN BROUGH</creatorcontrib><creatorcontrib>KAMALDEEP CHOHAN</creatorcontrib><creatorcontrib>KEI NORIMURA</creatorcontrib><creatorcontrib>SHINGO TOJO</creatorcontrib><creatorcontrib>PHILIP ABBOTT</creatorcontrib><creatorcontrib>STEPHEN THOM</creatorcontrib><creatorcontrib>ROGER VICTOR BONNERT</creatorcontrib><creatorcontrib>YOSHIAKI ISOBE</creatorcontrib><creatorcontrib>THOMAS MCINALLY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>STEPHEN BROUGH</au><au>KAMALDEEP CHOHAN</au><au>KEI NORIMURA</au><au>SHINGO TOJO</au><au>PHILIP ABBOTT</au><au>STEPHEN THOM</au><au>ROGER VICTOR BONNERT</au><au>YOSHIAKI ISOBE</au><au>THOMAS MCINALLY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVADOS DE ADENINAS, COMPOSICIONES FARMACÉUTICAS CONTENIÉNDOLOS, PROCEDIMIENTOS DE PREPARACIÓN Y APLICACIONES</title><date>2007-04-30</date><risdate>2007</risdate><abstract>La presente invención proporciona compuestos de fórmula donde R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R y R2 son como se define en la memoria descriptiva, a procesos para su preparación, a composiciones farmacéuticas que los contienen y a su uso en terapia. Se trata de compuestos 9-sustituidos-8-oxoadenina con propiedades inmuno modulantes que actúan vía TLR7 útiles para el tratamiento de enfermedades virales, alérgicas y cáncer.
The present invention provides compounds of formula (I) wherein R1, Y1, X1, Z1, X2, Y2, A, Y3, n, R and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DERIVADOS DE ADENINAS, COMPOSICIONES FARMACÉUTICAS CONTENIÉNDOLOS, PROCEDIMIENTOS DE PREPARACIÓN Y APLICACIONES |
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