ACETIL 2-HINDROXI-1,3-DIAMINOALCANOS

Se divulgan compuestos de la fórmula: dónde las varialbles Z, X, R15, R2, R3, y Rc son definidas aqui. Los compuestos divulgados aqui son inhibidores de enzima beta secreta y, por lo tanto, son útiles para el tratamiento de la enfermedad de Aazheimer y otras enfermedades caracterizadas por la deposi...

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Hauptverfasser: VARGHESE JOHN, SHON R. PULLEY, RUTH TENBRINK, ERIC T. BALDWIN, ROBERT HUGHES, MICHEL MAILLARD, JAMES T. BECK
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creator VARGHESE JOHN
SHON R. PULLEY
RUTH TENBRINK
ERIC T. BALDWIN
ROBERT HUGHES
MICHEL MAILLARD
JAMES T. BECK
description Se divulgan compuestos de la fórmula: dónde las varialbles Z, X, R15, R2, R3, y Rc son definidas aqui. Los compuestos divulgados aqui son inhibidores de enzima beta secreta y, por lo tanto, son útiles para el tratamiento de la enfermedad de Aazheimer y otras enfermedades caracterizadas por la deposición del péptido A beta en un mamífero. Disclosed are compounds of the formula: where variables Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ACETIL 2-HINDROXI-1,3-DIAMINOALCANOS
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