Nucleic acid molecules encoding anti-P-selectin antibodies

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff...

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Hauptverfasser: KLING DOROTHEE, STERN ANNE, KOPETZKI ERHARD, JANSEN-MOLENAAR MIRANDA, STUBENRAUCH KAY-GUNNAR, VAN DE WINKEL JAN, VAN VUGT MARTINE, STEINER BEAT, GRAUS YVO, REBERS FRANK, HIMBER JACQUES, BRAEMER PAMELA, PARREN PAUL
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creator KLING DOROTHEE
STERN ANNE
KOPETZKI ERHARD
JANSEN-MOLENAAR MIRANDA
STUBENRAUCH KAY-GUNNAR
VAN DE WINKEL JAN
VAN VUGT MARTINE
STEINER BEAT
GRAUS YVO
REBERS FRANK
HIMBER JACQUES
BRAEMER PAMELA
PARREN PAUL
description This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).
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These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130709&amp;DB=EPODOC&amp;CC=US&amp;NR=RE44359E$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130709&amp;DB=EPODOC&amp;CC=US&amp;NR=RE44359E$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KLING DOROTHEE</creatorcontrib><creatorcontrib>STERN ANNE</creatorcontrib><creatorcontrib>KOPETZKI ERHARD</creatorcontrib><creatorcontrib>JANSEN-MOLENAAR MIRANDA</creatorcontrib><creatorcontrib>STUBENRAUCH KAY-GUNNAR</creatorcontrib><creatorcontrib>VAN DE WINKEL JAN</creatorcontrib><creatorcontrib>VAN VUGT MARTINE</creatorcontrib><creatorcontrib>STEINER BEAT</creatorcontrib><creatorcontrib>GRAUS YVO</creatorcontrib><creatorcontrib>REBERS FRANK</creatorcontrib><creatorcontrib>HIMBER JACQUES</creatorcontrib><creatorcontrib>BRAEMER PAMELA</creatorcontrib><creatorcontrib>PARREN PAUL</creatorcontrib><title>Nucleic acid molecules encoding anti-P-selectin antibodies</title><description>This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Nucleic acid molecules encoding anti-P-selectin antibodies
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