Bispecific antigen binding protein complex and preparation methods of bispecific antibodies

Bispecific antigen binding protein complex and preparation methods of bispecific antibodies

A bispecific antigen binding protein complex comprising a first polypeptide comprising a first antigen binding site at an N terminus; a second polypeptide comprising a second antigen binding site at an N terminus; and a linker connecting the first polypeptide and the second polypeptide; wherein the...

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Hauptverfasser: Hwang SuJeong, Lee Jaeil, Kim Min-kyung, Lee JungWook
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Sprache:eng
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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creator Hwang SuJeong
Lee Jaeil
Kim Min-kyung
Lee JungWook
description A bispecific antigen binding protein complex comprising a first polypeptide comprising a first antigen binding site at an N terminus; a second polypeptide comprising a second antigen binding site at an N terminus; and a linker connecting the first polypeptide and the second polypeptide; wherein the linker comprises a tag at one terminus thereof, and wherein the tag is connected to a C-terminus of the first polypeptide or to an N-terminus of the second polypeptide, and comprises a cleavable amino acid sequence; as well as related compositions and methods.
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METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title Bispecific antigen binding protein complex and preparation methods of bispecific antibodies
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