Sphingolipid-polyalkylamine-oligonucleotide compounds

Provided herein are sphingolipid-polyalkylamine phosphoramidites, methods of generating sphingolipid-polyalkylamine-oligonucleotide compounds, pharmaceutical compositions comprising such compounds, and to methods of use thereof in treating cancer.

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Hauptverfasser: Avkin-Nachum Sharon, Hildesheim Jean, Kleinman Tirtsa, Truffert Jean-Christophe, Mathis Gerald
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Sprache:eng
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creator Avkin-Nachum Sharon
Hildesheim Jean
Kleinman Tirtsa
Truffert Jean-Christophe
Mathis Gerald
description Provided herein are sphingolipid-polyalkylamine phosphoramidites, methods of generating sphingolipid-polyalkylamine-oligonucleotide compounds, pharmaceutical compositions comprising such compounds, and to methods of use thereof in treating cancer.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Sphingolipid-polyalkylamine-oligonucleotide compounds
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