Chromatography ligand
The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon c...
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| creator | Engstrand Carina Glad Gunnar Maloisel Jean-Luc Johansson Bo-Lennart Johansson Hans J Forss Annika |
| description | The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies. |
| format | Patent |
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The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.</description><language>eng</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; SEPARATION ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180130&DB=EPODOC&CC=US&NR=9878266B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180130&DB=EPODOC&CC=US&NR=9878266B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Engstrand Carina</creatorcontrib><creatorcontrib>Glad Gunnar</creatorcontrib><creatorcontrib>Maloisel Jean-Luc</creatorcontrib><creatorcontrib>Johansson Bo-Lennart</creatorcontrib><creatorcontrib>Johansson Hans J</creatorcontrib><creatorcontrib>Forss Annika</creatorcontrib><title>Chromatography ligand</title><description>The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.</description><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>SEPARATION</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBB1zijKz00syU8vSizIqFTIyUxPzEvhYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxocGWFuYWRmZmTkbGRCgBAFSKIUE</recordid><startdate>20180130</startdate><enddate>20180130</enddate><creator>Engstrand Carina</creator><creator>Glad Gunnar</creator><creator>Maloisel Jean-Luc</creator><creator>Johansson Bo-Lennart</creator><creator>Johansson Hans J</creator><creator>Forss Annika</creator><scope>EVB</scope></search><sort><creationdate>20180130</creationdate><title>Chromatography ligand</title><author>Engstrand Carina ; Glad Gunnar ; Maloisel Jean-Luc ; Johansson Bo-Lennart ; Johansson Hans J ; Forss Annika</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US9878266B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2018</creationdate><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>SEPARATION</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>Engstrand Carina</creatorcontrib><creatorcontrib>Glad Gunnar</creatorcontrib><creatorcontrib>Maloisel Jean-Luc</creatorcontrib><creatorcontrib>Johansson Bo-Lennart</creatorcontrib><creatorcontrib>Johansson Hans J</creatorcontrib><creatorcontrib>Forss Annika</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Engstrand Carina</au><au>Glad Gunnar</au><au>Maloisel Jean-Luc</au><au>Johansson Bo-Lennart</au><au>Johansson Hans J</au><au>Forss Annika</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Chromatography ligand</title><date>2018-01-30</date><risdate>2018</risdate><abstract>The present invention relates to a chromatography ligand defined by the following formula R1-R2-N(R3)-R4-R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SEPARATION THEIR RELEVANT APPARATUS TRANSPORTING |
| title | Chromatography ligand |
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