Methods for treating bacterial infection

The present disclosure relates to molecules which function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphy...

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Hauptverfasser: McDowell Susan A, Sklar Larry A, Sammelson Robert E, Haynes Mark K
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creator McDowell Susan A
Sklar Larry A
Sammelson Robert E
Haynes Mark K
description The present disclosure relates to molecules which function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphylococcus aureus and Streptococcus pyogenes.
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PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Methods for treating bacterial infection
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