Acoustic perfusion devices

Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acous...

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Bibliographische Detailangaben
Hauptverfasser: Lipkens Bart, Chitale Kedar, Kennedy, III Thomas J, Presz, Jr. Walter M, Winiarski Lauren, Miller Erik, Ross-Johnsrud Benjamin
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn.