Hydroxy containing FXR (NR1H4) modulating compounds

Hydroxy containing FXR (NR1H4) modulating compounds

The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said...

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Hauptverfasser: Gege Christian, Kremoser Claus, Schmitt Aaron C, Kinzel Olaf
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator Gege Christian
Kremoser Claus
Schmitt Aaron C
Kinzel Olaf
description The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
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METALLURGY
ORGANIC CHEMISTRY
title Hydroxy containing FXR (NR1H4) modulating compounds
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