Substituted 1,2,4-triazines as tubulin inhibitors

Compounds of general formula (I), (II) (III) and (V) are described or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, for use in modulating microtubule polymerisation in a subject.

Bibliographische Detailangaben

Hauptverfasser:	Sikanyika Harrison, Burns Christopher John, Wilks Andrew Frederick, Fantino Emmanuelle, Harte Michael Francis
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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