Factor IXa inhibitors

The present invention provides a compound of Formula (I) where A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, emb...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Smith Cameron James, Guo Liangqin, Chan Tin-Yau, Tan John Qiang, Hirabayashi Tomokazu, Chen Yili, Balkovec James, Chackalamannil Samuel, Sherer Edward, Chen Yi-Heng, Sekioka Mika, Li Derun, Greenlee William John, Campeau Louis-Charles
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a compound of Formula (I) where A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.