Antibody-active agent conjugates and methods of use

The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates. The invention further provides methods for using the conjugates to deliver the active agent to a...

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Hauptverfasser: Chung Yunseo, Park Yun-Hee, Woo Sungho, Cho Jongun, Jung Doohwan, Kim Yongzu, Lee Hyangsook, Kwon Hyunjin, Kim Sunyoung, Kim Youngun, Park Taekyo, Oh Kyuman
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creator Chung Yunseo
Park Yun-Hee
Woo Sungho
Cho Jongun
Jung Doohwan
Kim Yongzu
Lee Hyangsook
Kwon Hyunjin
Kim Sunyoung
Kim Youngun
Park Taekyo
Oh Kyuman
description The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent).
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title Antibody-active agent conjugates and methods of use
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