Cosmetic compositions and methods

A cosmetic composition for topical application to skin is provided. The cosmetic composition includes vitamin B3 compound, a ricinoleate compound and a dermatologically acceptable carrier. The vitamin B3 compound and the ricinoleate beneficially or even synergistically up-regulate proteasomal protea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laughlin, II Leo Timothy, Sabino Michael Christopher, Hakozaki Tomohiro
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A cosmetic composition for topical application to skin is provided. The cosmetic composition includes vitamin B3 compound, a ricinoleate compound and a dermatologically acceptable carrier. The vitamin B3 compound and the ricinoleate beneficially or even synergistically up-regulate proteasomal protease activity as evidenced by a higher observed net luminescence value relative to the calculated net luminescence value in B16 melanoma cells.