Triazolopyridyl compounds as aldosterone synthase inhibitors
This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprisin...
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| creator | Cai Jaiqiang MacLean John Ratcliffe Paul Hoyt Scott B Carswell Emma London Clare Taylor Jerry Andrew Samanta Swapan Kumar Xiong Yusheng Cooke Andrew Kulkarni Bheemashankar A Bennett D. Jonathan |
| description | This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase. |
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This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170214&DB=EPODOC&CC=US&NR=9567333B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170214&DB=EPODOC&CC=US&NR=9567333B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Cai Jaiqiang</creatorcontrib><creatorcontrib>MacLean John</creatorcontrib><creatorcontrib>Ratcliffe Paul</creatorcontrib><creatorcontrib>Hoyt Scott B</creatorcontrib><creatorcontrib>Carswell Emma</creatorcontrib><creatorcontrib>London Clare</creatorcontrib><creatorcontrib>Taylor Jerry Andrew</creatorcontrib><creatorcontrib>Samanta Swapan Kumar</creatorcontrib><creatorcontrib>Xiong Yusheng</creatorcontrib><creatorcontrib>Cooke Andrew</creatorcontrib><creatorcontrib>Kulkarni Bheemashankar A</creatorcontrib><creatorcontrib>Bennett D. 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Jonathan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Cai Jaiqiang</au><au>MacLean John</au><au>Ratcliffe Paul</au><au>Hoyt Scott B</au><au>Carswell Emma</au><au>London Clare</au><au>Taylor Jerry Andrew</au><au>Samanta Swapan Kumar</au><au>Xiong Yusheng</au><au>Cooke Andrew</au><au>Kulkarni Bheemashankar A</au><au>Bennett D. Jonathan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Triazolopyridyl compounds as aldosterone synthase inhibitors</title><date>2017-02-14</date><risdate>2017</risdate><abstract>This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Triazolopyridyl compounds as aldosterone synthase inhibitors |
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